Results 71 to 80 of about 260,092 (192)

Effect of Green‐Synthesized Silver Nanoparticles From Nepeta pogonosperma and Astrodaucus persicus on the Reduction of Bap Gene Expression in Strong Biofilm‐Producing Acinetobacter baumannii Clinical Isolates

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Green‐synthesized silver nanoparticles from Nepeta pogonosperma and Astrodaucus persicus significantly inhibit biofilm formation and downregulate bap gene expression in multidrug‐resistant clinical isolates of Acinetobacter baumannii. This eco‐friendly approach offers a promising strategy to combat antimicrobial resistance.
Maedeh Kakavan, Mehrdad Gholami, Mohammad Ahanjan, Mohammad Ali Ebrahimzadeh, Abolfazl Hossein Nataj, Tahoora Mousavi, Hamid Reza Goli   +6 more
wiley   +1 more source

Half of rifampicin-resistant Mycobacterium tuberculosis complex isolated from tuberculosis patients in Sub-Saharan Africa have concomitant resistance to pyrazinamide.

, 2017
BackgroundBesides inclusion in 1st line regimens against tuberculosis (TB), pyrazinamide (PZA) is used in 2nd line anti-TB regimens, including in the short regimen for multidrug-resistant TB (MDR-TB) patients.
“Union short MDR-TB regimen study group”, Bouke Catherine de Jong, Kadanga, Abalo Essosimna, Ngabonziza, Jean Claude Semuto, Affolabi, Dissou, Sabine Houeto, Togo, Antieme Combo George, Ba, Fatoumata, Arnaud Trebucq, Abalo Essosimna Kadanga, Diarra, Bassirou, Elisa Tagliani, Riccardo Alagna, Thiam, Aliou, Willem Bram de Rijk, Aliou Thiam, Daneau, Geraldine, Diallo, Awa Ba, Géraldine Daneau, Houeto, Sabine, Rigouts, Leen, Anoumou Yaotsè Dagnra, Dissou Affolabi, de Rijk, Willem Bram, Jean Claude Semuto Ngabonziza, Fatoumata Ba, Ivan, Emil, Antieme Combo George Togo, Alagna, Riccardo, Valérie Schwoebel, Dagnra, Anoumou Yaotse, Awa Ba Diallo, null null, Tagliani, Elisa, Bassirou Diarra, Trebucq, Arnaud, Schwoebel, Valerie, de Jong, Bouke Catherine, Leen Rigouts, Emil Ivan   +39 more
core   +1 more source

Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management

MedComm, Volume 7, Issue 10, October 2026.
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley   +1 more source

Clinical Outcomes of a Digital Companion in Periodontal Care: A Randomised Controlled Trial

Journal of Clinical Periodontology, Volume 53, Issue 10, Page 1596-1609, October 2026.
ABSTRACT Aim To evaluate the efficacy of a digital health companion app as an adjunct to systematic periodontal therapy. Methods Seven German university dental centres conducted this multi‐centre randomised controlled trial. Adults with periodontitis (n = 194) were assigned to standard periodontal care with or without the Paro‐ComPas app.
Bettina Dannewitz, James Deschner, Christof Dörfer, Henrik Dommisch, Peter Eickholz, Lukas Förster, Lukasz Jablonowski, Neelam Lingwal, Stefan Listl, Maurice Rütters, Lina Weinert, Nihad El Sayed, the Paro‐ComPas Collaborators, Philipp Bani, Valentin Bartha, Thomas Beikler, Pablo Cores Ziskoven, Miriam Cyris, Ivana Elez, Maurice Fahn, Jens Göbel, Jana Gortschakow, Christian Graetz, Ahmad Haseeb, Oliver Heinze, Laurenz Hermans, Daniela Hoedke, Maren Kahl, Ti‐Sun Kim, Julian Kohlmüller, Denica Kuzmanova, Yola Meisel, Tugay Nebilir, Antares Outatzis, Gerd Schneider, Mario Schröder, Alexander Spies, Ingvi Spies, Claudia Springer, Leonie Staffeldt, Jessica Vasseur, Patrizia Winkler   +41 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, Volume 38, Issue 51, 11 September 2026.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Perceived Barriers to Accessing Tuberculosis Care Among Multidrug Resistant Tuberculosis (MDR-TB) Patients: A Qualitative Study in Indonesia [PDF]

, 2020
- Indonesia has one of the highest MDR-TB burdens in the world. The success rate of MDR-TB treatment in Indonesia is still low. Indonesia changed the health system policy, which is called the National Health Insurance,in 2013.
Tutik Kusmiati, -, R Endro Sulistyono, -, Lailatun, Ni'mah, Laily, Hidayati, Rr Dian, Tristiana   +4 more
core  

Gridlock from diagnosis to treatment of multidrug resistant tuberculosis (MDR-TB) in Tanzania: patients’ perspectives from a focus group discussion

BMC Public Health, 2020
Background Molecular diagnostics have revolutionized the diagnosis of multidrug resistant tuberculosis (MDR-TB). Yet in Tanzania we found delay in diagnosis with more than 70% of MDR-TB patients having a history of several previous treatment courses for ...
Stellah G. Mpagama, Mangi J. Ezekiel, Peter M. Mbelele, Anna M. Chongolo, Gibson S. Kibiki, Kristen Petros de Guex, Scott K. Heysell   +6 more
doaj   +1 more source

AI‐Assisted SERS in Bacterial Diagnosis and Antimicrobial Susceptibility Testing: Advances, Gaps, and Translational Pathways

Advanced Sensor Research, Volume 5, Issue 9, September 2026.
This review examines recent advances in integrating artificial intelligence (AI) with surface‐enhanced Raman spectroscopy (SERS) for the detection of pathogenic bacteria and evaluation of drug resistance phenotypes. Key challenges in clinical translation are critically discussed, along with prospective solutions and future research directions ...
Chen Liu, Yu Liu, Junlu Wang, Yujie Liu, Qijia Zhan, Jiangang Liu, Ruoping Chen, Kun Zhang   +7 more
wiley   +1 more source

Is HIV infection a risk factor for multi-drug resistant tuberculosis? A systematic review.

PLoS ONE, 2009
BackgroundTuberculosis (TB) is an important cause of human suffering and death. Human immunodeficiency virus (HIV), multi-drug resistant TB (MDR-TB), and extensive drug resistant tuberculosis (XDR-TB) have emerged as threats to TB control.
Sujit Suchindran, Emily S Brouwer, Annelies Van Rie   +2 more
doaj   +1 more source

High prevalence of primary multidrug resistant tuberculosis in persons with no known risk factors.

PLoS ONE, 2011
IntroductionIn high multidrug resistant (MDR) tuberculosis (TB) prevalence areas, drug susceptibility testing (DST) at diagnosis is recommended for patients with risk factors for MDR.
Larissa Otero, Fiorella Krapp, Cristina Tomatis, Carlos Zamudio, Francine Matthys, Eduardo Gotuzzo, Patrick Van der Stuyft, Carlos Seas   +7 more
doaj   +1 more source