Results 81 to 90 of about 260,092 (192)

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, Volume 13, Issue 51, 14 September 2026.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

MT‐RNR1 genotype testing for preventing aminoglycoside‐mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3002-3011, September 2026.
Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott, Sian Hilton, Cinzia Dello Russo, Nicola Booth, Simon Drysdale, Philip Howard, Stephen Hughes, Mallinath Chakraborty, Helen McDevitt, Charlotte Alston, Maya Desai, Mike Beadsworth, Adam Reynolds, Serim Min, Katherine Payne, Munir Pirmohamed, William G. Newman   +16 more
wiley   +1 more source

CTSs’ attitude towards MDR-TB.

, 2022
CTSs’ attitude towards MDR-TB.
J. Christo Heunis (13046945), N. Gladys Kigozi (13046948), Ernest Peresu (13046942), Diana De Graeve (11642908)   +3 more
core   +1 more source

Mitigating treatment failure of pulmonary pre-extensively drug-resistant tuberculosis: The role of new and repurposed drugs

Journal of Microbiology, Immunology and Infection
Background: Pre-extensively drug-resistant tuberculosis (pre-XDR-TB), defined as multidrug-resistant TB (MDR-TB) with additional resistance to any fluoroquinolone (FQ) is difficult to treat.
Yi-Wen Huang, Ming-Chih Yu, Chih-Bin Lin, Jen-Jyh Lee, Chou-Jui Lin, Shun-Tien Chien, Chih-Hsin Lee, Chen-Yuan Chiang   +7 more
doaj   +1 more source

Beyond the CE Mark: A Call to Action for Minimum CGM Accuracy Standards in Central and Eastern European Nations

Diabetes, Obesity and Metabolism, EarlyView.
Tomasz Klupa, Silvija Canecki‐Varžić, Adriana Ilavská, Andrej Janez, Sanja Klobučar, Mladen Krnić, Tatjana Milenkovic, Peter Novodvorský, Martin Prázný, Marko Simunovic, Jan Šoupal, Anca Pantea Stoian, Agnieszka Szadkowska, Tsvetelina Tankova, Tadej Battelino   +14 more
wiley   +1 more source

A Thiosemicarbazone Schiff Base and Its Titanium(IV) Complexes: Spectral Analysis, DFT Studies, and Biological Evaluation

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
DFT computations are used to analyze the electronic structure, stability, and reactivity profiles of a new Schiff base ligand and its Ti(IV) complexes and are characterized by elemental analysis, IR, 1H NMR, 13C NMR, and mass spectrometry and screened for antimicrobial activities against E. coli, S. aureus, ESBL, MRSA, Mtb, A.
Priyanka Ghanghas, Anshul Yadav, Astha Kamboj, Anita Choudhary, Manjinder Kour, Dinesh Kumar, Kavita Poonia   +6 more
wiley   +1 more source

MDR-TB electronic medical records abstraction tool.

MDR-TB electronic medical records abstraction tool.
J. Christo Heunis (13046945), N. Gladys Kigozi (13046948), Ernest Peresu (13046942), Diana De Graeve (11642908)   +3 more
core   +1 more source

Epidemic Levels of Drug Resistant Tuberculosis (MDR and XDR-TB) in a High HIV Prevalence Setting in Khayelitsha, South Africa. [PDF]

, 2010
BACKGROUND: Although multidrug-resistant tuberculosis (MDR-TB) is emerging as a significant threat to tuberculosis control in high HIV prevalence countries such as South Africa, limited data is available on the burden of drug resistant tuberculosis and ...
McDermid, Cheryl, Coetzee, David, Goemaere Eric, Azevedo, Virginia, John Simpson, McDermid Cheryl, Coetzee, D, Barnard, M, David Coetzee, van Cutsem Gilles, Coetzee, G, Coetzee David, Cox, Helen S, Goemaere, Eric, Cox, H S, Simpson, J, Goemaere, E, Simpson, John, Odelia Muller, Eric Goemaere, Helen S. Cox, Muller Odelia, van Cutsem, Gilles, Simpson John, Gerrit Coetzee, Muller, O, Marinus Barnard, Cox Helen S., Muller, Odelia, Cheryl McDermid, Virginia Azevedo, Gilles van Cutsem, McDermid, C, Azevedo Virginia, van Cutsem, G, Coetzee Gerrit, Barnard, Marinus, Azevedo, V, Coetzee, Gerrit, Barnard Marinus, Helen S Cox, Cox, Helen   +41 more
core   +2 more sources

Tuberculosis Misdiagnosed as Bronchogenic Carcinoma: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT The patient, a 77‐year‐old male smoker, presented to the Emergency Department with dyspnea, cough, fever, night sweats, and 12 kg weight loss, initially suggesting COPD or lung cancer. Chest CT revealed a right upper lobe mass, pleural effusion, and lymphadenopathy, prompting suspicion of malignancy.
Pejman Hosseinzadeh, Sara Samadi, Shirin Taraz Jamshidi, Sayed Mortaza Fayez, Mahnaz Mozdourian   +4 more
wiley   +1 more source

CTSs’ knowledge about MDR-TB.

, 2022
CTSs’ knowledge about MDR-TB.
J. Christo Heunis (13046945), N. Gladys Kigozi (13046948), Ernest Peresu (13046942), Diana De Graeve (11642908)   +3 more
core   +1 more source