Results 51 to 60 of about 273,177 (229)

Clinico-radiological Difference Section between Primary and Secondary MDR Pulmonary Tuberculosis [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Multidrug Resistant Tuberculosis (MDR-TB) is classified into primary and secondary type depending upon history of Anti-TB drug received in past. MDR-TB generally remains undetected in newly detected TB cases as the index of suspicion is low.
Deependra Kumar Rai, Alok
doaj   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

CTSs’ knowledge about MDR-TB.

, 2022
CTSs’ knowledge about MDR-TB.
J. Christo Heunis (13046945), N. Gladys Kigozi (13046948), Ernest Peresu (13046942), Diana De Graeve (11642908)   +3 more
core   +1 more source

MDR-TB in Pakistan: Challenges, efforts, and recommendations

Annals of Medicine & Surgery, 2022
Tuberculosis (TB), a global health concern is also a leading cause of mortality and morbidity across Pakistan affecting a major proportion of the population. The absence of an integrated system to control the spread of TB has led to a rise in multidrug resistant strains of TB (MDR-Tb) which do not exhibit any sensitivity towards the first line therapy ...
Khan, Mahad Ahmed, Bilal, Wajeeha, Asim, Hanzla, Rahmat, Zainab Syyeda, Essar, Mohammad Yasir, Ahmad, Shoaib   +5 more
openaire   +2 more sources

Operational challenges in diagnosing multi-drug resistant TB and initiating treatment in Andhra Pradesh, India. [PDF]

PLoS ONE, 2011
BACKGROUND: Revised National TB Control Programme (RNTCP), Andhra Pradesh, India. There is limited information on whether MDR-TB suspects are identified, undergo diagnostic assessment and are initiated on treatment according to the programme guidelines ...
Sarabjit S Chadha, B N Sharath, Kishore Reddy, Jyothi Jaju, P H Vishnu, Sreenivas Rao, Malik Parmar, Srinath Satyanarayana, Kuldeep Singh Sachdeva, Nevin Wilson, Anthony D Harries   +10 more
doaj   +1 more source

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

Advanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan, Soham Maity, Herbert Kavunja, Yuvarani Murali, Ting‐An Chen, Chang‐xin Huo, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +1 more source

Multiple Introductions of Multidrug-Resistant Tuberculosis into Households, Lima, Peru

Emerging Infectious Diseases, 2011
Two cases of multidrug-resistant tuberculosis (MDR TB) in a household are assumed to reflect within-household transmission. However, in high-incidence areas of MDR TB, secondary cases may arise through exposure to MDR TB in the community. To estimate the
Ted Cohen, Megan B. Murray, Ibrahim Abubakar, Zibiao Zhang, Alexander Sloutsky, Fernando Arteaga, Katiuska Chalco, Molly F. Franke, Mercedes C. Becerra   +8 more
doaj   +1 more source

Predicting outcomes in equine peritonitis: Multivariable analysis of admission and post‐admission data from a UK hospital population

Equine Veterinary Journal, EarlyView.
Abstract Background Peritonitis is life‐threatening, and limited information exists regarding outcomes and predictors of survival. Objectives To report short‐ and long‐term outcomes in horses diagnosed with peritonitis and identify factors associated with survival. Study Design Retrospective observational. Methods Data were obtained for horses admitted
E. K. Kopec, H. Carslake, D. C. Archer, B. Morris, A. Wilson   +4 more
wiley   +1 more source

Multidrug-Resistant Tuberculosis 
Outbreak among US-bound Hmong 
Refugees, Thailand, 2005

Emerging Infectious Diseases, 2008
In January 2005, tuberculosis (TB), including multidrug-resistant TB (MDR TB), was reported among Hmong refugees who were living in or had recently immigrated to the United States from a camp in Thailand.
John E. Oeltmann, Jay K. Varma, Luis Ortega, Yecai Liu, Thomas O’Rourke, Maria Cano, Theresa A. Harrington, Sean Toney, Warren Jones, Samart Karuchit, Lois Diem, Dhanida Rienthong, Jordan W. Tappero, Kashef Ijaz, Susan A. Maloney   +14 more
doaj   +1 more source

Comparative Diagnostic Performance of Three Commercial Real‐Time PCR Assays for the Detection of Mycobacterium tuberculosis Complex in Bronchial Washing Specimens: A Large Retrospective Study

Journal of Clinical Laboratory Analysis, EarlyView.
This large retrospective study compared the diagnostic performance of three commercial real‐time PCR assays (AdvanSure TB/NTM, Cobas MTB, and Xpert MTB/RIF) for MTBC detection in 3348 bronchial washing specimens. In a head‐to‐head comparison of 740 specimens, the Cobas MTB and Xpert MTB/RIF assays showed markedly higher sensitivity than the AdvanSure ...
Jimyung Kim, Yumi Park
wiley   +1 more source