Results 81 to 90 of about 63,034 (284)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Structural Properties of Twisted Reed-Solomon Codes with Applications to Cryptography
, 2018 We present a generalisation of Twisted Reed-Solomon codes containing a new large class of MDS codes. We prove that the code class contains a large subfamily that is closed under duality.
Beelen, Peter +3 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
MDR codes and self-dual codes on Cartesian product codes
Tongxin xuebao, 2010 A Cartesian product code of the linear codes C1 , , C s in 1 , ,Z r Z rs was defined. According to the theorem of submodulo isomorphism, the relationship between the rank of the Cartesian product code C1 × C 2 × × Cs over Z r1 × Z r2 × × Zrsand C1 , C 2,
LIU Xiu-sheng
doaj +2 more sources
An evaluation of machine learning and latent semantic analysis in text sentiment classification
Technical Transactions, 2020 In this paper, we compare the following machine learning methods as classifiers for sentiment analysis: k – nearest neighbours (kNN), artificial neural network (ANN), support vector machine (SVM), random forest.
Miazga Justyna, Hachaj Tomasz
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
On the construction of reversible DNA codes over $ F_{4^{2m}} $ via $ T^n $-set codes
AIMS MathematicsThe main objective of this paper is to introduce a new approach for constructing reversible and reversible DNA codes over the finite fields $ F_{4^{2m}} $, $ m\ge 1 $ from any given polynomials by utilizing $ T^n $-set codes.
Elif Segah Oztas +5 more
doaj +1 more source
IEEE Transactions on Information Theory, 2022 An improved Singleton-type upper bound is presented for the list decoding radius of linear codes, in terms of the code parameters [n,k,d] and the list size L. L-MDS codes are then defined as codes that attain this bound (under a slightly stronger notion of list decodability), with 1-MDS codes corresponding to ordinary linear MDS codes.
openaire +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source