Results 21 to 30 of about 24,597 (236)

Avirulent Marek's disease virus type 1 strain 814 vectored vaccine expressing avian influenza (AI) virus H5 haemagglutinin induced better protection than turkey herpesvirus vectored AI vaccine. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Herpesvirus of turkey (HVT) as a vector to express the haemagglutinin (HA) of avian influenza virus (AIV) H5 was developed and its protection against lethal Marek's disease virus (MDV) and highly pathogenic AIV (HPAIV) challenges was ...
Hongyu Cui   +10 more
doaj   +1 more source

A FN-MdV pathway and its role in cerebellar multimodular control of sensorimotor behavior

open access: yesNature Communications, 2020
The cerebellum is crucial for various associative sensorimotor behaviors. Delay eyeblink conditioning (DEC) depends on the simplex lobule-interposed nucleus (IN) pathway, yet it is unclear how other cerebellar modules cooperate during this task. Here, we
Xiaolu Wang   +4 more
semanticscholar   +1 more source

The sulphated polysaccharides extract ulvans from Ulva armoricana limits Marek’s disease virus dissemination in vitro and promotes viral reactivation in lymphoid cells

open access: yesBMC Veterinary Research, 2022
Background Marek’s disease (MD) is a highly contagious lymphoproliferative disease of chickens caused by an alphaherpesvirus, Marek’s disease virus (MDV). MD is presently controlled by systematic vaccination of animals, which protects efficiently against
Frédérick Bussy   +4 more
doaj   +1 more source

Marek's Disease Virus and Reticuloendotheliosis Virus Coinfection Enhances Viral Replication and Alters Cellular Protein Profiles

open access: yesFrontiers in Veterinary Science, 2022
Coinfection with Marek's disease virus (MDV) and reticuloendotheliosis virus (REV) causes synergistic pathogenic effects and serious losses to the poultry industry.
Xusheng Du   +4 more
doaj   +1 more source

Marek's disease virus prolongs survival of primary chicken B-cells by inducing a senescence-like phenotype.

open access: yesPLoS Pathogens, 2021
Marek's disease virus (MDV) is an alphaherpesvirus that causes immunosuppression and deadly lymphoma in chickens. Lymphoid organs play a central role in MDV infection in animals. B-cells in the bursa of Fabricius facilitate high levels of MDV replication
Laëtitia Trapp-Fragnet   +7 more
doaj   +1 more source

Characterization of a Novel Viral Interleukin 8 (vIL-8) Splice Variant Encoded by Marek’s Disease Virus

open access: yesMicroorganisms, 2021
Marek’s disease virus (MDV) is a highly cell-associated oncogenic alphaherpesvirus that causes lymphomas in various organs in chickens. Like other herpesviruses, MDV has a large and complex double-stranded DNA genome.
Yu You   +4 more
doaj   +1 more source

Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E2 [PDF]

open access: yes, 2019
Marek’s disease virus (MDV) causes deadly lymphoma and induces an imbalance of the lipid metabolism in infected chickens. Here, we discovered that MDV activates the fatty acid synthesis (FAS) pathway in primary chicken embryo fibroblasts (CEFs).
Behboudi, Shahriar   +3 more
core   +1 more source

MDVs: Spare the SOD and Spoil the Bug [PDF]

open access: yesCell Host & Microbe, 2018
Mitochondrial reactive oxygen species are important anti-microbial weapons utilized by phagocytes of the innate immune system. In this issue of Cell Host and Microbe, Abuaita et al. (2018) show that in macrophages, mitochondrial-derived vesicles deliver the superoxide dismutase Sod2 to bacteria-containing phagosomes to produce hydrogen peroxide and ...
Syed Saad, Hussain, David F, Kashatus
openaire   +2 more sources

HISTORY AND CURRENT STATUS OF MAREK'S DISEASE IN TURKEYS

open access: yesGerman Journal of Veterinary Research, 2021
Marek’s disease (MD), caused by a highly contagious and oncogenic herpesvirus, causes immunosuppression and tumours in chickens. Although several reports on occurring lymphomas (MD-like conditions) in turkeys were published in the past less attention has
Awad Shehata   +2 more
doaj   +1 more source

Marek's Disease Virus Type 2 (MDV-2)-Encoded MicroRNAs Show No Sequence Conservation with Those Encoded by MDV-1 [PDF]

open access: yesJournal of Virology, 2007
ABSTRACTMicroRNAs (miRNAs) are increasingly being recognized as major regulators of gene expression in many organisms, including viruses. Among viruses, members of the familyHerpesviridaeaccount for the majority of the currently known virus-encoded miRNAs.
Yongxiu Yao   +7 more
semanticscholar   +3 more sources

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