Results 11 to 20 of about 21,268 (210)

Trials for isolation and identification of Marek's disease virus (MDV) in layer chicken farms vaccinated with MDV vaccines exhibiting MDV-like symptoms in Egypt [PDF]

open access: yesBenha Veterinary Medical Journal
Marek's disease virus (MDV) is a lymphoproliferative neuropathic disease affecting domestic fowl. Despite intensive vaccination, Egyptian poultry farms continue to experience recurrent infections of MDV.
Alaa H. Ibrahim   +3 more
openaire   +2 more sources

TNFRSF11B modulates Marek's disease virus infection by regulating apoptosis in chicken embryo fibroblasts. [PDF]

open access: yesFront Vet Sci
IntroductionMarek’s disease, caused by the oncogenic Marek’s disease virus (MDV), remains a major threat to poultry production. Host immune responses and apoptosis pathways play critical roles in MDV pathogenesis, yet the underlying mechanisms are not ...
Zheng G, Yang Y, Du Y, Liu Y, Lian L.
europepmc   +2 more sources

Differential Replication and Cytokine Response between Vaccine and Very Virulent Marek’s Disease Viruses in Spleens and Bursas during Latency and Reactivation

open access: yesViruses, 2022
Marek’s disease virus (MDV) infection results in Marek’s disease (MD) in chickens, a lymphoproliferative and oncogenic deadly disease, leading to severe economic losses. The spleen and bursa are the most important lymphoid and major target organs for MDV
Bo Jiang   +8 more
doaj   +1 more source

US3 Serine/Threonine Protein Kinase from MDV-1, MDV-2, and HVT Differentially Regulate Viral Gene Expression and Replication

open access: yesMicroorganisms, 2021
Gallid alphaherpesvirus 2 (GaHV-2), commonly known as Marek’s disease virus type 1 (MDV-1), is an oncogenic avian alphaherpesvirus, and along with its close relatives—Gallid alphaherpesvirus 3 (GaHV-3) or MDV-2 and Meleagrid alphaherpesvirus 1 (MeHV-1 ...
Yifei Liao   +5 more
doaj   +1 more source

RIOK3-Mediated Akt phosphorylation facilitates synergistic replication of Marek’s disease and reticuloendotheliosis viruses

open access: yesVirulence, 2022
Co-infection of Marek’s disease virus (MDV) and reticuloendotheliosis virus (REV) synergistically drives disease progression, yet little is known about the mechanism of the synergism.
Xusheng Du   +4 more
doaj   +1 more source

Marek's disease virus US3 protein kinase phosphorylates chicken HDAC 1 and 2 and regulates viral replication and pathogenesis.

open access: yesPLoS Pathogens, 2021
Marek's disease virus (MDV) is a potent oncogenic alphaherpesvirus that elicits a rapid onset of malignant T-cell lymphomas in chickens. Three MDV types, including GaHV-2 (MDV-1), GaHV-3 (MDV-2) and MeHV-1 (HVT), have been identified and all encode a US3
Yifei Liao   +3 more
doaj   +1 more source

Alterations of the MDV oncogenic regions in an MDV transformed lymphoblastoid cell line [PDF]

open access: yesMolecular Pathology, 2002
Lymphoblastoid cell lines derived from Marek's disease virus (MDV) induced tumours have served as models of MDV latency and transformation. They are stable and can be cultured with no detectable MDV genomic alterations upon repeated passaging. An MDV transformed lymphoblastoid T cell line (T9 cell line) has been reported to contain a disrupted MDV ...
Le Rouzic, E.   +5 more
openaire   +3 more sources

Latest Insights into Unique Open Reading Frames Encoded by Unique Long (UL) and Short (US) Regions of Marek’s Disease Virus

open access: yesViruses, 2021
Marek’s disease virus (MDV) is an oncogenic avian alphaherpesvirus whose genome consists of unique long (UL) and short (US) regions that are flanked by inverted repeat regions.
Yifei Liao   +2 more
doaj   +1 more source

Vitamin Compatibility with the Marek’s Disease Vaccine

open access: yesPoultry, 2023
In ovo injection of the Marek’s disease (MD) vaccine (MDV) has been widely practiced in commercial US hatcheries. However, the MDV is very sensitive and may not be compatible with some nutrients when administered together by in ovo injection.
Seyed Abolghasem Fatemi   +3 more
doaj   +1 more source

MDVs: Spare the SOD and Spoil the Bug [PDF]

open access: yesCell Host & Microbe, 2018
Mitochondrial reactive oxygen species are important anti-microbial weapons utilized by phagocytes of the innate immune system. In this issue of Cell Host and Microbe, Abuaita et al. (2018) show that in macrophages, mitochondrial-derived vesicles deliver the superoxide dismutase Sod2 to bacteria-containing phagosomes to produce hydrogen peroxide and ...
Syed Saad, Hussain, David F, Kashatus
openaire   +2 more sources

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