Results 11 to 20 of about 6,080 (184)
Viruses, 2022 Marek’s disease virus (MDV) infection results in Marek’s disease (MD) in chickens, a lymphoproliferative and oncogenic deadly disease, leading to severe economic losses. The spleen and bursa are the most important lymphoid and major target organs for MDV
Bo Jiang +8 more
doaj +1 more source
Microorganisms, 2021 Gallid alphaherpesvirus 2 (GaHV-2), commonly known as Marek’s disease virus type 1 (MDV-1), is an oncogenic avian alphaherpesvirus, and along with its close relatives—Gallid alphaherpesvirus 3 (GaHV-3) or MDV-2 and Meleagrid alphaherpesvirus 1 (MeHV-1 ...
Yifei Liao +5 more
doaj +1 more source
Virulence, 2022 Co-infection of Marek’s disease virus (MDV) and reticuloendotheliosis virus (REV) synergistically drives disease progression, yet little is known about the mechanism of the synergism.
Xusheng Du +4 more
doaj +1 more source
PLoS Pathogens, 2021 Marek's disease virus (MDV) is a potent oncogenic alphaherpesvirus that elicits a rapid onset of malignant T-cell lymphomas in chickens. Three MDV types, including GaHV-2 (MDV-1), GaHV-3 (MDV-2) and MeHV-1 (HVT), have been identified and all encode a US3
Yifei Liao +3 more
doaj +1 more source
Alterations of the MDV oncogenic regions in an MDV transformed lymphoblastoid cell line [PDF]
Molecular Pathology, 2002 Lymphoblastoid cell lines derived from Marek's disease virus (MDV) induced tumours have served as models of MDV latency and transformation. They are stable and can be cultured with no detectable MDV genomic alterations upon repeated passaging. An MDV transformed lymphoblastoid T cell line (T9 cell line) has been reported to contain a disrupted MDV ...
Le Rouzic, E. +5 more
openaire +3 more sources
Viruses, 2021 Marek’s disease virus (MDV) is an oncogenic avian alphaherpesvirus whose genome consists of unique long (UL) and short (US) regions that are flanked by inverted repeat regions.
Yifei Liao +2 more
doaj +1 more source
Vitamin Compatibility with the Marek’s Disease Vaccine
Poultry, 2023 In ovo injection of the Marek’s disease (MD) vaccine (MDV) has been widely practiced in commercial US hatcheries. However, the MDV is very sensitive and may not be compatible with some nutrients when administered together by in ovo injection.
Seyed Abolghasem Fatemi +3 more
doaj +1 more source
Microorganisms, 2021 Promyelocytic leukemia protein nuclear bodies (PML-NBs) are dynamic nuclear structures, shown to be important for herpesvirus replication; however, their role in regulating Marek’s disease virus (MDV) infection has not been studied.
Yifei Liao +2 more
doaj +1 more source
MDVs: Spare the SOD and Spoil the Bug [PDF]
Cell Host & Microbe, 2018 Mitochondrial reactive oxygen species are important anti-microbial weapons utilized by phagocytes of the innate immune system. In this issue of Cell Host and Microbe, Abuaita et al. (2018) show that in macrophages, mitochondrial-derived vesicles deliver the superoxide dismutase Sod2 to bacteria-containing phagosomes to produce hydrogen peroxide and ...
Syed Saad, Hussain, David F, Kashatus
openaire +2 more sources
Avirulent Marek's disease virus type 1 strain 814 vectored vaccine expressing avian influenza (AI) virus H5 haemagglutinin induced better protection than turkey herpesvirus vectored AI vaccine. [PDF]
PLoS ONE, 2013 BACKGROUND: Herpesvirus of turkey (HVT) as a vector to express the haemagglutinin (HA) of avian influenza virus (AIV) H5 was developed and its protection against lethal Marek's disease virus (MDV) and highly pathogenic AIV (HPAIV) challenges was ...
Hongyu Cui +10 more
doaj +1 more source