Results 21 to 30 of about 10,431 (233)

Mapping QTL Associated with Resistance to Avian Oncogenic Marek’s Disease Virus (MDV) Reveals Major Candidate Genes and Variants

bioRxiv, 2020
Marek’s Disease (MD) represents a significant global economic and animal welfare issue. Marek’s Disease Virus (MDV) is a highly contagious oncogenic and highly immune-suppressive alpha-herpes virus, which infects chickens, causing neurological effects ...
Jacqueline Smith, E. Lipkin, M. Soller, J. Fulton, D. Burt   +4 more
semanticscholar   +1 more source

Analysis of the evolution and transmission dynamics of the field MDV in China during the years 1995-2020, indicating the emergence of a unique cluster with the molecular characteristics of vv+MDV that has become endemic in southern China.

Transboundary and Emerging Diseases, 2020
Marek's disease (MD) continues to threaten the sustainability of the world poultry industry. In this study, the sequences of the meq gene of 220 MDV strains isolated during the years 1964-2020 were analyzed, including 50 from our group plus 170 isolates ...
Qiaomu Deng, M. Shi, Qiuhong Li, Peikun Wang, Min Li, Wen Wang, Yanli Gao, Haijuan Li, Lulu Lin, Teng Huang, P. Wei   +10 more
semanticscholar   +1 more source

Efficient Marek's disease virus (MDV) and herpesvirus of turkey infection of the QM7 cell line that does not contain latent MDV genome

Avian Pathology, 2014
Marek's disease virus (MDV; also known as Gallid herpesvirus 2, MDV-1) causes oncogenic disease in chickens producing clinical signs that include lymphomas, visceral tumours, nerve lesions, and immunosuppression. MDV vaccines are widely used and mostly produced using primary cells: chicken embryo fibroblast cells, duck embryo fibroblast cells, chicken ...
Sing Rong, D. Wheeler, F. Weber
semanticscholar   +3 more sources

Marek's disease virus prolongs survival of primary chicken B-cells by inducing a senescence-like phenotype.

PLoS Pathogens, 2021
Marek's disease virus (MDV) is an alphaherpesvirus that causes immunosuppression and deadly lymphoma in chickens. Lymphoid organs play a central role in MDV infection in animals. B-cells in the bursa of Fabricius facilitate high levels of MDV replication
Laëtitia Trapp-Fragnet, Julia Schermuly, Marina Kohn, Luca D Bertzbach, Florian Pfaff, Caroline Denesvre, Benedikt B Kaufer, Sonja Härtle   +7 more
doaj   +1 more source

Marek's Disease Virus and Reticuloendotheliosis Virus Coinfection Enhances Viral Replication and Alters Cellular Protein Profiles

Frontiers in Veterinary Science, 2022
Coinfection with Marek's disease virus (MDV) and reticuloendotheliosis virus (REV) causes synergistic pathogenic effects and serious losses to the poultry industry.
Xusheng Du, Defang Zhou, Jing Zhou, Jingwen Xue, Ziqiang Cheng   +4 more
doaj   +1 more source

Characterization of a Novel Viral Interleukin 8 (vIL-8) Splice Variant Encoded by Marek’s Disease Virus

Microorganisms, 2021
Marek’s disease virus (MDV) is a highly cell-associated oncogenic alphaherpesvirus that causes lymphomas in various organs in chickens. Like other herpesviruses, MDV has a large and complex double-stranded DNA genome.
Yu You, Ibrahim T. Hagag, Ahmed Kheimar, Luca D. Bertzbach, Benedikt B. Kaufer   +4 more
doaj   +1 more source

Avirulent Marek's disease virus type 1 strain 814 vectored vaccine expressing avian influenza (AI) virus H5 haemagglutinin induced better protection than turkey herpesvirus vectored AI vaccine. [PDF]

PLoS ONE, 2013
BACKGROUND: Herpesvirus of turkey (HVT) as a vector to express the haemagglutinin (HA) of avian influenza virus (AIV) H5 was developed and its protection against lethal Marek's disease virus (MDV) and highly pathogenic AIV (HPAIV) challenges was ...
Hongyu Cui, Hongbo Gao, Xianlan Cui, Yan Zhao, Xingming Shi, Qiaoling Li, Shuai Yan, Ming Gao, Mei Wang, Changjun Liu, Yunfeng Wang   +10 more
doaj   +1 more source

Tình hình nhiễm virus gây bệnh Marek trên gà thả vườn ở thành phố Cần Thơ

Tạp chí Khoa học Đại học Cần Thơ, 2022
Khảo sát tỷ lệ nhiễm virus gây bệnh Marek (MDV) trên các đàn gà thả vườn đã được thực hiện ở thành phố Cần Thơ. Tổng số 353 mẫu nang lông được thu thập từ 50 đàn gà chưa tiêm vaccine phòng bệnh Marek ở các huyện Phong Điền, Cờ Đỏ, Thới Lai và Vĩnh Thạnh.
Huỳnh Ngọc Trang, Hồ Thị Việt Thu   +1 more
doaj   +1 more source

The sulphated polysaccharides extract ulvans from Ulva armoricana limits Marek’s disease virus dissemination in vitro and promotes viral reactivation in lymphoid cells

BMC Veterinary Research, 2022
Background Marek’s disease (MD) is a highly contagious lymphoproliferative disease of chickens caused by an alphaherpesvirus, Marek’s disease virus (MDV). MD is presently controlled by systematic vaccination of animals, which protects efficiently against
Frédérick Bussy, Sylvie Rémy, Matthieu Le Goff, Pi Nyvall Collén, Laëtitia Trapp-Fragnet   +4 more
doaj   +1 more source

HISTORY AND CURRENT STATUS OF MAREK'S DISEASE IN TURKEYS

German Journal of Veterinary Research, 2021
Marek’s disease (MD), caused by a highly contagious and oncogenic herpesvirus, causes immunosuppression and tumours in chickens. Although several reports on occurring lymphomas (MD-like conditions) in turkeys were published in the past less attention has
Awad Shehata, Dörte Lüschow, Hafez Hafez   +2 more
doaj   +1 more source