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Despite its previous classification as a gammaherpesvirus, primarily due to its lymphotropism, Marek's disease virus (MDV), an oncogenic avian herpesvirus, is phylogenetically more related to the "neurotropic" alphaherpesviruses, characterized by its prototype, herpes simplex virus (HSV) (Buckmaster et al., 1988, J. Gen. Virol. 69, 2033-2042).
Brunovskis, Peter, Velicer, Leland F.
openaire +2 more sources
Role of Marek’s Disease Virus (MDV)-Encoded U S 3 Serine/Threonine Protein Kinase in Regulating MDV Meq and Cellular CREB Phosphorylation [PDF]
MDV is a potent oncogenic herpesvirus that induces T-cell lymphoma in infected chickens. Marek's disease continues to have a significant economic impact on the poultry industry worldwide. U S 3 encoded by alphaherpesviruses is a multifunctional kinase involved in the regulation of various cellular pathways. Using an
Liao, Yifei +5 more
openaire +4 more sources
Marek’s disease virus (MDV), an avian alphaherpesvirus, infects chickens, transforms CD4+ T cells, and induces immunosuppression early during infection.
Nitin Kamble +6 more
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La tecnología LiDAR es una de las fuentes de información geográfica que permite ob- tener puntos de coordenadas incluyendo la altura con mayor precisión. Una de las principales aplicaciones que tiene LiDAR es en el sector forestal, pero que en Colom- bia
Cristian Danilo Martinez Tobon +2 more
doaj
: Marek's disease virus (MDV) causes malignant lymphomas in chickens (Marek's disease; MD). Although MD has caused significant economic losses to the poultry industry, currently, its occurrence in the field is effectively controlled by vaccination ...
Shiro Murata +6 more
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The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu +9 more
wiley +1 more source
Ground‐based robotic remote sensing for standardized biodiversity monitoring in coastal habitats
Illustrated workflow of the proposed citizen‐to‐robot monitoring pipeline: (i) expert‐validated citizen observations are translated into AI models, (ii) deployed on a ground‐based robotic platform for proximal sensing of coastal dune habitats, (iii) enabling standardized detection of ecological targets (e.g., Pancratium maritimum & Brithys crini), and (
Giovanni Di Lorenzo +5 more
wiley +1 more source
Application of lentinan in suppression of Marek's disease virus infection
Marek's disease virus (MDV) is an extremely widespread avian immunosuppressive virus. In recent years, many reports have shown that there are still cases of MDV infection and immunosuppression after immunization with the vaccine. Consequently, there is a
Qiming Gao +6 more
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Background Marek's disease virus (MDV), which is widely considered to be a natural model of virus-induced lymphoma, has the potential to cause tremendous losses in the poultry industry.
Wang Ming, Chi Xiaojing, Wang Xiaojia
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