Results 61 to 70 of about 10,431 (233)

Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation

Advanced Science, EarlyView.
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir, Yagmur Ozendi, Gokhan Burcin Kubat, Keshav K. Singh   +3 more
wiley   +1 more source

Tubocapsenolide A Overcomes Oxaliplatin Resistance in Colorectal Cancer by Targeting PLK1 to Impair CEP55–ESCRT‐Associated Vesicular Damage Clearance

Advanced Science, EarlyView.
Oxaliplatin‐resistant colorectal cancer cells utilize a previously unappreciated PLK1‐CEP55‐ESCRT‐driven vesicular extrusion mechanism to clear L‐OHP‐induced cellular damage. The natural withanolide Tubocapsenolide A directly targets and inhibits PLK1 to disrupt this specific damage‐clearance machinery. This blockade induces severe nucleolar stress and
Yueying Yang, Jing Liang, Lu Wang, Hongyan Zhang, Zhiruo Zhang, Yang Liu, Rui Zhu, Wen Xu, Shaohua Xu, Dejuan Sun, Ke Xiang, Yali Wang, Zhimin Fan, Zheng Wang, Hua Li, Lixia Chen   +15 more
wiley   +1 more source

Histone Methylation Analysis and Pathway Predictions in Chickens after MDV Infection

PLoS ONE, 2012
Marek's disease (MD) is a lymphoproliferative disease in chicken induced by Marek's disease virus (MDV). Although studies have focused on the genetic differences between the resistant and susceptible chicken, less is known about the role of epigenetic ...
Juan Luo, Apratim Mitra, Fei Tian, Shuang Chang, Huan-Ming Zhang, Kai-Rong Cui, Ying Yu, Ke-Ji Zhao, Jiuzhou Song   +8 more
semanticscholar   +1 more source

APLICACIÓN DE DATOS LiDAR EN LA ESTIMACIÓN DEL VOLUMEN FORESTAL EN EL PARQUE METROPOLITANO BOSQUE SAN CARLOS

Ciencia e Ingeniería Neogranadina, 2013
La tecnología LiDAR es una de las fuentes de información geográfica que permite ob- tener puntos de coordenadas incluyendo la altura con mayor precisión. Una de las principales aplicaciones que tiene LiDAR es en el sector forestal, pero que en Colom- bia
Cristian Danilo Martinez Tobon, Jhon Eric Aunta Duarte, Jorge Alberto Valero Fandiño   +2 more
doaj  

A quadruplex real-time PCR assay combined with a conventional PCR for the differential detection of Marek’s disease virus vaccines and field strains

Frontiers in Veterinary Science, 2023
To evaluate the effect of the vaccine and differentiate vaccine from virulent MDV, a new quadruplex real-time PCR assay based on TaqMan probes was developed to differentiate and accurately quantify HVT, CVI988 and virulent MDV-1.
Shaopeng Wu, Shaopeng Wu, Shaopeng Wu, Tian Ding, Tian Ding, Tian Ding, Hongxia Shao, Hongxia Shao, Hongxia Shao, Kun Qian, Kun Qian, Kun Qian, Jianqiang Ye, Jianqiang Ye, Jianqiang Ye, Aijian Qin, Aijian Qin, Aijian Qin   +17 more
doaj   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Clonal Structure of Rapid-Onset MDV-Driven CD4+ Lymphomas and Responding CD8+ T Cells

PLoS Pathogens, 2011
Lymphoid oncogenesis is a life threatening complication associated with a number of persistent viral infections (e.g. EBV and HTLV-1 in humans). With many of these infections it is difficult to study their natural history and the dynamics of tumor ...
W. Mwangi, Lorraine P. Smith, S. Baigent, Richard K. Beal, V. Nair, A. Smith   +5 more
semanticscholar   +1 more source

Cumulative electroconvulsive therapy sessions and focal epilepsy: A nationwide cohort study in Japan

Epilepsia Open, EarlyView.
Abstract Objective Electroconvulsive therapy (ECT) is widely used for severe psychiatric disorders, yet concerns remain regarding possible epileptogenic effects associated with prolonged or repeated exposure. We examined the association between cumulative ECT sessions and focal epilepsy in a nationwide Japanese cohort.
Masahiro Hata, Yuki Miyazaki, Hisaki Omori, Shun Takahashi, Manabu Ikeda   +4 more
wiley   +1 more source

Application of lentinan in suppression of Marek's disease virus infection

Poultry Science
Marek's disease virus (MDV) is an extremely widespread avian immunosuppressive virus. In recent years, many reports have shown that there are still cases of MDV infection and immunosuppression after immunization with the vaccine. Consequently, there is a
Qiming Gao, Kongda Zhu, Wanli Sun, Shun Li, Yixin Wang, Shuang Chang, Peng Zhao   +6 more
doaj   +1 more source

The Requirement of Glycoprotein C for Interindividual Spread Is Functionally Conserved within the Alphaherpesvirus Genus (Mardivirus), but Not the Host (Gallid)

Viruses, 2021
Marek’s disease (MD) in chickens is caused by Gallid alphaherpesvirus 2, better known as MD herpesvirus (MDV). Current vaccines do not block interindividual spread from chicken-to-chicken, therefore, understanding MDV interindividual spread provides ...
Widaliz Vega-Rodriguez, Nagendraprabhu Ponnuraj, Maricarmen Garcia, Keith W. Jarosinski   +3 more
doaj   +1 more source