Results 41 to 50 of about 4,749,978 (243)

Some Results on Super Mean Graphs [PDF]

, 2009
Approaching topics such as labeling, Smarandachely super mean labeling, Smarandachely super m-mean graph, super mean labeling, super mean ...
Nagarajan, A., Vasuki, R.
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Constructing and Validating a Geometric–Organic Index for Road Networks in Qing Dynasty County Cities

ISPRS International Journal of Geo-Information
The position of urban road networks along the spectrum from geometric order to organic growth reflects the long-term tension between institutional planning and adaptive accommodation to local conditions, yet systematic quantification of this continuum in
Longyin Teng, Lin Li, Jian Dai
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

A Type of Mean Values of Several Positive Numbers with Two Parameters [PDF]

, 2006
In this article, a type of mean values of several positive numbers with two parameters are defined by using the generalized Vandermonde determinant, some basic properties of them are given, and several inequalities for some mean values including the ...
Zhang, Zhi-Hua, Qi, Feng, Xiao, Zhen-Gang   +2 more
core   +3 more sources

Revisiting each fracture size and spatial pattern: Inference from rock mass surface to interior

Journal of Rock Mechanics and Geotechnical Engineering
Estimating fracture size is a fundamental aspect of rock engineering. However, determining the most probable diameter (MPD) from a fracture's surface trace remains challenging in the scientific community.
Yongqiang Liu, Jianping Chen, Jiewei Zhan   +2 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

From Free Wrapping to Contact Gripping: Mechanical Response of a Vacuum-Driven Soft Actuator

Actuators
Soft robots adapt to object shapes through structural compliance; wrapping actuators generate gripping force through continuous enveloping contact. This study presents a vacuum-driven pneumatic helical spring (PHS) actuator and a simplified analytical ...
Wumian Zhao, Xinbo Chen, Chunjie Wei, Kunming Zhu, Jiantao Yao   +4 more
doaj   +1 more source

Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling to Predict the Impact of CYP2C9 Genetic Polymorphisms, Co-Medication and Formulation on the Pharmacokinetics and Pharmacodynamics of Flurbiprofen

Pharmaceutics, 2020
Physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) models can serve as a powerful framework for predicting the influence as well as the interaction of formulation, genetic polymorphism and co-medication on the pharmacokinetics and ...
Ioannis Loisios-Konstantinidis, Rodrigo Cristofoletti, Masoud Jamei, David Turner, Jennifer Dressman   +4 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source