Results 91 to 100 of about 4,058,790 (257)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Lectures on mean curvature flows
, 2002 "Mean curvature flow" is a term that is used to describe the evolution of a hypersurface whose normal velocity is given by the mean curvature. In the simplest case of a convex closed curve on the plane, the properties of the mean curvature flow are ...
Zhu, Xi-Ping, Xi-Ping Zhu
core +1 more source
Concentrated Curvature for Mean Curvature Estimation
, 2010 We present a mathematical result that allows computing the discrete mean curvature of a polygonal surface from the so-called concentrated curvature generally used for Gaussian curvature estimation.
MAGILLO, PAOLA +2 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Brain asymmetry is globally different in males and females: exploring cortical volume, area, thickness, and mean curvature. [PDF]
Cereb Cortex, 2023 Dumitru ML.
europepmc +1 more source
Surfaces of Revolution with Constant Mean Curvature in Galilean 3-Space
MathematicsRevolution surfaces with zero mean curvature in the Galilean 3-space have been extensively studied in the literature. However, revolution surfaces with non-zero constant mean curvature in this geometric setting have not yet been investigated in a ...
İsmet Gölgeleyen +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Detection of Corneal Ectasia Using OCT Maps of Pachymetry and Posterior Surface Mean Curvature. [PDF]
J Refract Surg, 2022 Pavlatos E +4 more
europepmc +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Local Well-Posedness of Skew Mean Curvature Flow for Small Data in d ≥ 4 Dimensions. [PDF]
Commun Math Phys, 2022 Huang J, Tataru D.
europepmc +1 more source