Results 91 to 100 of about 3,233,557 (302)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Ground state solutions for the Hénon prescribed mean curvature equation

open access: yesAdvances in Nonlinear Analysis, 2018
In this paper, we consider the analogous of the Hénon equation for the prescribed mean curvature problem in ℝN{{\mathbb{R}^{N}}}, both in the Euclidean and in the Minkowski spaces. Motivated by the studies of Ni and Serrin [W. M. Ni and J.
Azzollini Antonio
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

The mean curvature at the first singular time of the mean curvature flow

open access: yesAnnales de l'Institut Henri Poincaré C, Analyse non linéaire, 2010
Consider a family of smooth immersions F( \cdot ,t):M^{n}\rightarrow \mathbb{R}^{n + 1} of closed hypersurfaces in \mathbb{R}^{n + 1} moving by the mean curvature flow \frac{\partial F(p,t)}{\partial t} = −
Le, Nam Q., Sesum, Natasa
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

An algorithm for Mean Curvature Motion

open access: yesInterfaces and Free Boundaries, Mathematical Analysis, Computation and Applications, 2004
We propose in this paper a new algorithm for computing the evolution by mean curvature of a hypersurface. Our algorithm is a variant of the variational approach of Almgren, Taylor and Wang [2]. We show that it approximates, as the time-step goes to zero, the generalized motion(in the sense of barriers or viscosity solutions). The results still hold for
openaire   +3 more sources

Phon Mean oral history recording

open access: yes, 2001
An audio recording of an oral history of Phon Mean about fleeing Cambodia with her family at age ten and coming to the United States. She talks about life in Cambodia when she was a child and then about life in the U.S., including school, her first job ...
Mean, Phon
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Rotational Hypersurfaces in S3(r)R Product Space

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2017
We consider rotational hypersurfaces in S3(r) R product space of five dimensional Euclidean space E5. We calculate the mean curvature and the Gaussian curvature, and give some results.
Erhan Güler, Ömer Kişi
doaj   +1 more source

On area comparison and rigidity involving the scalar curvature [PDF]

open access: yes
In this thesis we study the effects of lower bounds for the curvature of a Riemannian manifold M on the geometry and topology of closed, minimal hypersurfaces.
Moraru, Vlad
core  

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