Results 81 to 90 of about 117,814 (315)

The mean curvature at the first singular time of the mean curvature flow

Annales de l'Institut Henri Poincaré C, Analyse non linéaire, 2010
Consider a family of smooth immersions F( \cdot ,t):M^{n}\rightarrow \mathbb{R}^{n + 1} of closed hypersurfaces in \mathbb{R}^{n + 1} moving by the mean curvature flow \frac{\partial F(p,t)}{\partial t} = −
Le, Nam Q., Sesum, Natasa
openaire   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Fattening in mean curvature flow

32 pages, 2 figures.
Ilmanen, Tom, White, Brian
openaire   +2 more sources

Formal asymptotic expansions for symmetric ancient ovalsin mean curvature flow

Networks and Heterogeneous Media, 2013
We provide formal matched asymptotic expansions for ancient convex solutions to MCF. The formal analysis leading to the solutions is analogous to that for the generic MCF neck pinch in [1].
Sigurd Angenent
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Cosmological meaning of geometric curvatures

Filomat, 2020
In this paper, we analyzed the physical meaning of scalar curvatures for a generalized Riemannian space. It is developed the Madsen?s formulae for pressures and energy-densities with respect to the corresponding energy-momentum tensors. After that, the energy-momentum tensors, pressures, energy-densities and state-parameters are analyzed ...
openaire   +3 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Immersions of bounded mean curvature

Archiv der Mathematik, 1979
Archiv Der ...
Hasanis, T., Koutroufiotis, D.
openaire   +2 more sources

Ground state solutions for the Hénon prescribed mean curvature equation

Advances in Nonlinear Analysis, 2018
In this paper, we consider the analogous of the Hénon equation for the prescribed mean curvature problem in ℝN{{\mathbb{R}^{N}}}, both in the Euclidean and in the Minkowski spaces. Motivated by the studies of Ni and Serrin [W. M. Ni and J.
Azzollini Antonio
doaj   +1 more source