Results 81 to 90 of about 703,577 (334)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

A survey on Inverse mean curvature flow in ROSSes

open access: yesComplex Manifolds, 2017
In this survey we discuss the evolution by inverse mean curvature flow of star-shaped mean convex hypersurfaces in non-compact rank one symmetric spaces.
Pipoli Giuseppe
doaj   +1 more source

Lectures on mean curvature flow [PDF]

open access: yes, 2014
A family of hypersurfaces evolves by mean curvature flow if the velocity at each point is given by the mean curvature vector. Mean curvature flow is the most natural evolution equation in extrinsic geometry, and has been extensively studied ever since ...
Haslhofer, Robert
core  

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Hamiltonian mean curvature flow [PDF]

open access: yesInternational Journal of Contemporary Mathematical Sciences, 2013
Let ( , ) be a compact Riemann surface with constant curvature c. In this work, we proved that the mean curvature flow of a given Hamiltonian diffeomorphism on provides a smooth path in Ham( ), the group of all Hamiltonian diffeomorphisms of .
Leonard Todjihounde, Djideme F. Houenou
openaire   +3 more sources

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Constant Mean Curvature Spacelike Surfaces in Lorentzian Warped Products

open access: yesAdvances in Mathematical Physics, 2015
We characterize the spacelike slices of a Lorentzian warped product as the only constant mean curvature spacelike surfaces under suitable geometrical and physical assumptions.
Juan A. Aledo, Rafael M. Rubio
doaj   +1 more source

On the extension of axially symmetric volume flow and mean curvature flow [PDF]

open access: yesarXiv, 2013
We study the provenance of singularity formation under mean curvature flow and volume preserving mean curvature flow in an axially symmetric setting. We prove that if the mean curvature is uniformly bounded on any finite time interval, then no singularities can develop during that time under both mean curvature flow and volume preserving mean curvature
arxiv  

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

open access: yesMolecular Oncology, EarlyView.
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso   +12 more
wiley   +1 more source

MCnet: A Neural Network Method for Mean Curvature Optimization on Image Surfaces

open access: yesIEEE Access
Mean curvature is fundamentally important for various research fields, including differential geometry in mathematics, cell membrane modeling in biophysics and image processing in computer vision.
Zhili Wei, Wenming Tang, Yuanhao Gong
doaj   +1 more source

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