Results 71 to 80 of about 577,330 (363)
Approximation of mean curvature flow with generic singularities by smooth flows with surgery [PDF]
Advances in Mathematics, 2021 J. Daniels-Holgate
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A finite element error analysis for axisymmetric mean curvature flow [PDF]
arXiv.org, 2019 We consider the numerical approximation of axisymmetric mean curvature flow with the help of linear finite elements. In the case of a closed genus-1 surface, we derive optimal error bounds with respect to the $L^2$-- and $H^1$--norms for a fully discrete
J. Barrett, K. Deckelnick, R. Nürnberg
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
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Mean Curvature Type Flow with Perpendicular Neumann Boundary Condition inside a Convex Cone
Abstract and Applied Analysis, 2014 We investigate the evolution of hypersurfaces with perpendicular Neumann boundary condition under mean curvature type flow, where the boundary manifold is a convex cone.
Fangcheng Guo, Guanghan Li, Chuanxi Wu
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Mathematical and Computational Applications, 2019 We study a variational problem for hypersurfaces in the Euclidean space with an anisotropic surface energy. An anisotropic surface energy is the integral of an energy density that depends on the surface normal over the considered hypersurface, which was ...
Miyuki Koiso
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Guan–Li type mean curvature flow for free boundary hypersurfaces in a ball [PDF]
Communications in analysis and geometry, 2019 In this paper we introduce a Guan-Li type volume preserving mean curvature flow for free boundary hypersurfaces in a ball. We give a concept of star-shaped free boundary hypersurfaces in a ball and show that the Guan-Li type mean curvature flow has long ...
Guofang Wang, C. Xia
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
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Diffuse-interface approximation and weak–strong uniqueness of anisotropic mean curvature flow
European Journal of Applied MathematicsThe purpose of this paper is to derive anisotropic mean curvature flow as the limit of the anisotropic Allen–Cahn equation. We rely on distributional solution concepts for both the diffuse and sharp interface models and prove convergence using relative ...
Tim Laux +2 more
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PLoS ONE, 2015 PurposeFlow diverters (FD) are increasingly being considered for treating large or giant wide-neck aneurysms. Clinical outcome is highly variable and depends on the type of aneurysm, the flow diverting device and treatment strategies.
Jinyu Xu +7 more
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