Results 71 to 80 of about 264,591 (279)

Mean curvature flow, orbits, moment maps [PDF]

open access: yesTransactions of the American Mathematical Society, 2003
Given a compact Riemannian manifold together with a group of isometries, we discuss MCF of the orbits and some applications: e.g., finding minimal orbits. We then specialize to Lagrangian orbits in Kaehler manifolds. In particular, in the Kaehler-Einstein case we find a relation between MCF and moment maps which, for example, proves that the minimal ...
openaire   +6 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Nonexistence of mean curvature flow solitons with polynomial volume growth immersed in certain semi-Riemannian warped products

open access: yesAdvances in Nonlinear Analysis
Our purpose is to establish nonexistence results concerning complete noncompact mean curvature flow solitons with polynomial volume growth immersed in certain semi-Riemannian warped products, under mild constraints on the warping and soliton functions ...
Batista Márcio   +3 more
doaj   +1 more source

Modelling Free Flow Speed on Two-Lane Rural Highways in Bosnia and Herzegovina

open access: yesPromet (Zagreb), 2014
Free flow speed is used as a parameter in transportation planning and capacity analysis models, as well as speed-flow diagrams. Many of these models suggest estimating free flow speed according to measurements from similar highways, which is not a ...
Ivan Lovrić   +2 more
doaj   +1 more source

Swampland, gradient flow and infinite distance

open access: yesJournal of High Energy Physics, 2020
In the first part of this paper we will work out a close and so far not yet noticed correspondence between the swampland approach in quantum gravity and geometric flow equations in general relativity, most notably the Ricci flow.
Alex Kehagias   +2 more
doaj   +1 more source

Mean Curvature Flow with Boundary

open access: yes, 2019
We develop a theory of surfaces with boundary moving by mean curvature flow. In particular, we prove a general existence theorem by elliptic regularization, and we prove boundary regularity at all positive times under very mild hypotheses.
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Uniform flow distribution to stacked parallel disk channels in a disk shape small-capacity SOFC stack model

open access: yesNihon Kikai Gakkai ronbunshu, 2020
The design of a flow distribution to multiple branch channels is one of the key factors to realize the flow uniformity in a fuel cell stack. Especially for a disk-shape solid oxide fuel cell (SOFC) stack, it is necessary to clarify the optimum structure ...
Kazumi TSUNODA   +2 more
doaj   +1 more source

Mean curvature flow on Ricci solitons [PDF]

open access: yesJournal of Physics A: Mathematical and Theoretical, 2009
19 ...
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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