Results 61 to 70 of about 428,360 (302)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
IEEE AccessIn this study, comprehensive approximate Bayesian computation (ABC) technique is explored, and develop for an innovative model. We practically demonstrate approximate Bayesian computation (ABC)-Gibbs scheme using Kolmogorov-Smirnov as distance function ...
Mustapha Muhammad +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
On some tests for exponentiality based on the mean residual life function
Kuwait Journal of Science, 2016 We build on the work of Aly (1983) and Jammalamadaka & Taufer (2006) to developnew tests for exponentiality based on the mean residual life function.
Suja Mansour Aboukhamseen +1 more
doaj
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Modeling Mean Residual Life Function Using Scale Mixtures
, 2008 The mean residual life function (mrlf) of a subject is defined as the expected remaining (residual) lifetime of the subject given that the subject has survived up to a given time point.
Liu, Shufang
core
Bayesian Nonparametric Gamma Mixtures For Mean Residual Life Inference [PDF]
, 2013 In survival analysis interest lies in modeling data that describe the time to a particular event. Informative functions, namely the hazard function and mean residual life function, can be obtained from the model's distribution function.
Poynor, Valerie Ann
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Extending the Kumaraswamy distribution: properties and applications
Frontiers in Applied Mathematics and StatisticsIn this study, we propose a new extension of the Kumaraswamy distribution, termed the PNJKumaraswamy Distribution, developed using the PNJ transformation technique.
Mahvish Jan +3 more
doaj +1 more source