Results 91 to 100 of about 3,763,617 (312)

Association between adiponectin and heart failure risk in the Physicians' Health Study [PDF]

, 2014
Limited data are available on the association between adiponectin and incident heart failure. In the current ancillary study to the Physicians' Health Study, we used a prospective nested-case control design to examine whether plasma adiponectin ...
Djoussé, Luc, Gaziano, J. Michael, Glynn, Robert, Hanson, Naomi Q., Tsai, Michael Y., Wilk, Jemma B.   +5 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

RELIABILITY ANALYSIS OF COMPUTER NETWORKS USING PARAMETRIC FAILURE CRITERIA

Статистика и экономика, 2016
A mathematical model, which allows to obtain expressions for the determination of parameters of reliability of computer ne t w o rks co n sis t i n g o f i den t i c al recoverable elements.
Oleg A. Tkachev
doaj   +1 more source

Option Pricing on Renewable Commodity Markets [PDF]

Options markets on agricultural commodities with maturities that exceed 13 months seldom trade. Our hypothesis is that this market failure is due to the absence of an accurate option pricing model for commodities where mean reversion can be expected ...
Hart, Chad E., Hayes, Dermot J., Jin, Na, Lence, Sergio H.   +3 more
core   +1 more source

Penentuan Jadwal Preventive Maintenance Mesin-mesin Di Stasiun Gilingan (Studi Kasus Pg. Lestari Kertosono) [PDF]

, 2015
Kebutuhan gula semakin meningkat seiring dengan peningkatan jumlah penduduk dan peningkatan pendapatan masyarakat, Untuk memproduksi gula dalam jumlah yang banyak, diperlukan suatu alat yang dapat membantu dan mempercepat proses produksi tersebut yakni ...
Revitasari, C. (Cindy), Novareza, O. (Oyong), Darmawan, Z. (Zefry)   +2 more
core   +1 more source

Effect of home-based walking on performance and quality of life in patients with heart failure

, 2012
Introduction: Chronic heart failure defined as the inability of the heart to meet the demands of the tissues, which results in symptoms of fatigue or dyspnoea on energy progressing to dyspnoea at rest.
Abbasi, A., Ahmadi, F., Fayazi, S., Zarea, K.   +3 more
core   +1 more source

Neuropsychiatric symptoms following metal-on-metal implant failure with cobalt and chromium toxicity [PDF]

, 2017
Background: There were at least 31,171 metal-on-metal (MoM) hip implants in the UK between 2003 and 2011. Some of these were subject to failure and widescale recalls and revisions followed.
A Beraudi, AF Pizon, Agency for Toxic Substances and Disease Registry, AJ Smith, American Psychiatric Association, AT Beck, AW Schaffer, B Green, Ben Green, D Pelclova, DA Jones, DJ Paustenbach, Emily Griffiths, GA Afolaranmi, J Crawford, JC Anthony, JJ Devlin, JP Dick, JR Campbell, L Gerhardsson, L Lasa, MA Lambert, Medicines and Healthcare Products Regulatory Agency, MF Folstein, MJ Clark, RE Andrews, SM Bradberry, Solomon Almond, X Mao, Z Krejpcio   +29 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Employing the Rayleigh Distribution to Estimate the Reliability of a French Fries Cutting Machine and Using a Markov Chain to Estimate the Probability of Transitioning from One State to Another for the Short and Long Term

Tikrit Journal of Administrative and Economic Sciences
In this study we used two methods to estimate the hazard of the cutting machine of French fries which are reliability analysis with Rayleigh distribution and Markov chine to estimate the probability transition from a state to another, the data that had ...
Asraa Sadoon Alwan, Hindreen Abdullah Taher, Heshu Othman F. Mahmood   +2 more
doaj   +1 more source