Results 81 to 90 of about 3,763,617 (312)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
IEEE Access, 2019 The main purpose of this paper is to design a scientific-based probabilistic model based on Markov chains, to calculate reliability indicators, such as mean time between failure (MTBF) and mean time to failure (MTTF) based on probabilities, to compute ...
Simona-Vasilica Oprea +3 more
doaj +1 more source
Analysis of Node Failures in High Performance Computers Based on System Logs [PDF]
, 2015 The growth in size and complexity of HPC systems leads to a rapid increase of their failure rates. In the near future, it is expected that the mean time between failures of HPC systems becomes too short and that current failure recovery mechanisms will ...
Ciorba, Florina M. +3 more
core
Laparoscopic sleeve gastrectomy in adolescents with or without syndromic obesity: two years follow-up [PDF]
, 2017 Introduction Childhood obesity is an emerging health problem. Surgical treatment of obese adolescents, particularly those affected by congenital syndrome, represents a controversial issue.
ABBATINI, FRANCESCA +6 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Mathematical and Computer Modelling, 1995 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kimura, M., Yamada, S., Osaki, S.
openaire +1 more source
Availability and mean time between failures of redundant systems with random maintenance of subsystems [PDF]
It is shown how the availability and MTBF (Mean Time Between Failures) of a redundant system with subsystems maintenanced at the points of so-called stationary renewal processes can be determined from the distributions of the intervals between ...
Schneeweiss, W.
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Granular Impact: A Grain-scale Approach
, 2015 This work summarizes a series of studies on two-dimensional granular impact, where an intruding object strikes a granular material at high speed. Many previous studies on granular impact have used a macroscopic force law, which is dominated by an ...
Allen +49 more
core +1 more source