Results 61 to 70 of about 1,360,767 (269)
Accelerated Degradation Model of Nonlinear Wiener Process Based on Fixed Time Index
Mathematics, 2019 In the process of extrapolating a lifetime distribution function under normal storage conditions through nonlinear accelerated degradation data, time indexes under the normal storage conditions are usually set to the mean value of time indexes under ...
Hanzhong Liu +3 more
doaj +1 more source
, 2016 A significant percentage of production costs is the maintenance costs, and analysis of maintenance costs could to achieve greater productivity and competitiveness. With this is mind, the maintenance of machines and installations is considered as an essential part of organizational functions and applying effective strategies causes significant added ...
Jalal Soleimannejad +3 more
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
IEEE Access, 2019 The main purpose of this paper is to design a scientific-based probabilistic model based on Markov chains, to calculate reliability indicators, such as mean time between failure (MTBF) and mean time to failure (MTTF) based on probabilities, to compute ...
Simona-Vasilica Oprea +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Estimation of Mean Time between Failures of a Two Tandem Mill of a Sugar Plant
International Journal for Research in Applied Science and Engineering Technology, 2022 Abstract: When minutes of down-time can negatively impact the bottom line of a business, it is crucial that the physical infrastructure supporting be reliable. The equipment reliability can be achieved with a solid understanding of mean time between failures.
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Study on Mean Time Between Failures Prediction Algorithms Based on Weibull Distribution
IOP Conference Series: Earth and Environmental Science, 2020 Abstract The system reliability is significant importance because it is involved into most stages of the whole life-cycle of product. According to the existing literature, MTBF is the most frequently used index to indicate the system reliability.
Peitong wang, Jinwei Fan, Zhongsheng Li
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source