Results 241 to 250 of about 984,374 (339)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The Current Landscape of Sacred Moments Research: Reconsidering Meaning, Relationality, and Well-Being in Health Care. [PDF]

J Gen Fam Med
Watari T, Saint S.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Meaning in Life and Professional Identity Among Nursing Students: The Parallel Mediating Role of Death Attitudes and the Moderating Role of Peer Support. [PDF]

J Multidiscip Healthc
Gu Y, Zhao Y, Yang X, Lu Z, Wu D, Xie J.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The mediating effect of meaning in life on fear of death and attitudes toward caring for the dying among oncology nurses. [PDF]

BMC Nurs
Lai L, Wang W, Zhao J, Xin M, Fu X, Chen M, Qin H.   +6 more
europepmc   +1 more source

Exploring meaning in culture: Insights from meaning-centered psychotherapy in Aotearoa, New Zealand. [PDF]

Palliat Support Care
Clayden C, Wells A, Applebaum AJ, Reynolds L.   +3 more
europepmc   +1 more source

The longitudinal effects of faith and meaning on quality of life in US women with breast cancer undergoing chemotherapy. [PDF]

Palliat Support Care
Conti EC, Ratcliff CG, Chaoul A, Cohen L.   +3 more
europepmc   +1 more source

The influence of school climate on teachers' well-being indicators in China: a serial mediation model. [PDF]

BMC Psychol
Liao W, Yan C, Yang L, Xu H.
europepmc   +1 more source