Results 81 to 90 of about 984,374 (339)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Control, identity and meaning in voluntary work : the case of the Royal National Lifeboat Institution [PDF]

open access: yes
Organization studies, including studies of control and identity, has to date been almost exclusively concerned with organizations where work is paid for. By contrast, this thesis considers the dynamics of control and identity when work is unpaid, through
O'Toole, Michelle
core  

The consumption of work: representations and interpretations of the meaning of work at a UK university [PDF]

open access: yes, 2017
This paper focuses on representations of the nexus of work, meaning and consumption as experienced by university students. We develop an empirically based argument that the meaning of work is being constructed as an object of consumption on a British ...
Taylor, Scott; id_orcid   +7 more
core   +3 more sources

Loss and Resilience in the Time of COVID‐19: Meaning Making, Hope, and Transcendence

open access: yesFamily Process, 2020
This article addresses the many complex and traumatic losses wrought by the COVID‐19 pandemic. In contrast to individually based, symptom‐focused grief work, a resilience‐oriented, systemic approach with complex losses contextualizes the distress and ...
F. Walsh
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Job-related stress and burnout

open access: yes, 2002
Occupational stress is a topic of substantial interest to organizational researchers and managers, as well as society at large. Stress arising from work conditions can be pervasive and significant in its impact on individuals, their families and ...
Cooper, Cary L.   +1 more
core  

Relying on AI at work reduces self-efficacy, ownership, and meaning while active collaboration mitigates the effects

open access: yesScientific Reports
Artificial intelligence (AI) promises major productivity gains, but it also raises fundamental questions about how technology can reshape people’s relationship to their work.
Elena Hayoung Lee   +3 more
doaj   +1 more source

The mediating role of meaning in work in promoting teachers’ technology integration

open access: yesFrontiers in Education
Teachers’ integration of technology has been a critical focus for both teachers and researchers over the past three decades. This emphasis has intensified due to the COVID-19 pandemic, where technology integration has become a key factor in the success ...
Dholina Inang Pambudi   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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