Results 131 to 140 of about 27,363 (307)
If emotions provide information relevant to personal meaning, then people with a greater sense of clarity about their emotions may possess some advantages in finding meaning in their lives.
Robinson, Michael +3 more
core +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Older people with incurable cancer : Existential meaning-making from a life-span perspective
, 2016 Objective: An increasing number of older people in Western countries are living with incurable cancer, receiving palliative care from specialized healthcare contexts.
Danbolt, Lars J. +3 more
core +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
An empirical investigation of the relationship between existential meaning-in-life and racial prejudice [PDF]
, 2006 Thesis (MA (Psychology))--University of Stellenbosch, 2006.This study had two main objectives: Firstly, to investigate the relationship between existential meaning-in-life and racial prejudice amongst students at Stellenbosch University; secondly to ...
Niemand, Johannes Rust
core
The existential status of the meaning of human life
Sovremennye Issledovaniâ Socialʹnyh ProblemBackground. The world of the present is quite complex and contradictory, having become transparent and fragile. The society described with the prefix «post» has exacerbated the problem of the essence of man, putting on the agenda the question of the ...
Manushak A. Egikyan
doaj +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
A Quest for Communitas [Elektronisk resurs] : Rethinking Mediated Memory Existentially
, 2014 Despite the fragmentation of audience behaviour and the pluralization of platforms within the media cultures of the digital age, cultural memory practices retain an important feature: They echo a basic existential quest for communitas.
Lagerkvist, Amanda,
core
From epistemological truth to existential meaning in cognitive narrative psychotherapy
The notion of truth is discussed from the standpoint of narrative cognitive psychotherapy. The dominant clinical epistemological framework, based on the search for truth, needs to be replaced by an existential framework emphasizing the construction of ...
Gonçalves, Óscar F.
core +1 more source