Results 71 to 80 of about 252,569 (305)

Caring for insiderness: Phenomenologically informed insights that can guide practice [PDF]

, 2014
Understanding the "insider" perspective has been a pivotal strength of qualitative research. Further than this, within the more applied fields in which the human activity of "caring" takes place, such understanding of "what it is like" for people from ...
Dahlberg, Karin, Galvin, Kathleen T., Todres, Les   +2 more
core   +2 more sources

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Journal of Process Types in Transitivity System [PDF]

, 2012
This study concentrates on the analysis of process types in transitivity system, which is a very important branch of Halliday\u27s Systemic Functional Grammar. The writer turns to this theory because of its belief that language can be considered as human
Alfiana, Y. (Yuni)
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

FACTORIAL STRUCTURE OF THE EXISTENCE SCALE [PDF]

research articleExistential meaning in life is becoming an increasingly important measure of personal assessment. In search of a suitable instrument to measure existential meaning, the authors reviewed several measures.
Brouwers, André, Tomic, Welko
core  

Process, eventuality and wieder/again [PDF]

, 2009
This paper argues for a scopal explanation of the readings of the adverb wieder (‘again’). It is the syntactic entity that wieder is related to which determines whether the repetitive or the restitutive reading obtains.
Pittner, Karin
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

The Hermeneutics of Values in the Novel A Portion of Chicken Noodles Before Dying as a Source of Existential Counseling Intervention

Bisma The Journal of Counseling
Many individuals experience confusion regarding the meaning and purpose of life due to the pressure of social comparison, making it difficult for them to fully understand themselves. This study aims to analyze the existential values in the novel Seporsi
Rahmawati, Budi Purwoko, Evi Winingsih, Bakhrudin All Habsy   +3 more
doaj   +1 more source