Results 111 to 120 of about 478,112 (306)

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

The Meaning of Life Among Caregivers [PDF]

open access: bronze, 2021
Inna Rozentsvit
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Revealing the heterogeneity of meaning in life and its relationship with creativity among university students: A latent profile analysis study

open access: yesActa Psychologica
Meaning in life is crucial for university students' exploration and affirmation of their self-identity, while creativity, as a positive trait, may influence individuals' search for and perception of meaning in life.
Haodong Su, Tongtong Ye, Xiaoguang Wu
doaj   +1 more source

Treatment Adherence, Meaning in Life and Affects in Quality of Life of HIV/AIDS Patients

open access: green, 2019
Ana Catarina Reis   +3 more
openalex   +2 more sources

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