Results 81 to 90 of about 709,129 (333)

Relevance and meaningfulness: Student perspectives on the highly talented international business professional profile

open access: yesJournal of the European Honors Council, 2020
Competencies deemed relevant and meaningful by international business professionals and implemented in IB education, still do not produce work-ready graduates. This may be because these competencies are not perceived as relevant or meaningful by students.
Petra van Heugten   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Comparison of Effective and Non-Effective Icons in the Searching Module Concerning Familiarity and Meaningfulness in Azarakhsh, Simorgh and Nika Digital Libraries [PDF]

open access: yesکتابداری و اطلاع‌رسانی, 2016
Purpose: The present study aimed to compare effective and non-effective icons in the searching module with regard to familiarity and meaningfulness in Azarakhsh, Simorgh and Nika digital libraries.
Mahdieh Mirzabegi   +2 more
doaj  

Viewing Meaningful Work Through the Lens of Time

open access: yesFrontiers in Psychology, 2020
Authors have paid considerable attention to how to define the meaningful work construct. This has led to providing comprehensive definitions in the light of different theoretical frameworks that reflect a degree of contestation within the field.
Francesco Tommasi   +2 more
doaj   +1 more source

Measurement and meaningfulness

open access: yesACTA IMEKO, 2014
<p>This is a reissue of a paper which appeared in ACTA IMEKO 1985, Proceedings of the 10th World Congress of the International Measurement Confederation, "New measurement technology to serve mankind", 22.-26.4.1985, Prague, pp. 319-333.</p><p>The question raised in this paper is: What is the meaning of a statement in which reference ...
openaire   +3 more sources

Meaningful Matches in Stereovision [PDF]

open access: yesIEEE Transactions on Pattern Analysis and Machine Intelligence, 2012
IEEE Transactions on Pattern Analysis and Machine Intelligence 99, Preprints (2011) 1 ...
Neus Sabater   +2 more
openaire   +4 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Mystery in Relation to Meaningfulness [PDF]

open access: yes, 2023
Something that is difficult to understand or explain can be described as a mystery. Mysteries excite curiosity, wonder and may even lead individuals to feel a sense of awe. This can be both good and bad but depending on how one interprets the experience,
Gonzalez, Candilaria Martha
core   +1 more source

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