Results 71 to 80 of about 3,609,059 (246)

Fruit recognition based on pulse coupled neural network and genetic Elman algorithm application in apple harvesting robot

open access: yesInternational Journal of Advanced Robotic Systems, 2020
In order to improve the harvesting efficiency of apple harvesting robot, this article presents an apple recognition method based on pulse coupled neural network and genetic Elman neural network (GA-Elman).
Weikuan Jia   +6 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

A nighttime image enhancement method based on Retinex and guided filter for object recognition of apple harvesting robot

open access: yesInternational Journal of Advanced Robotic Systems, 2018
In order to improve the working efficiency of robot promptly picking ripe apples, the harvesting robot must have the ability of continuous recognition and operation at night. Nighttime apple image has many dark spaces and shadows with low resolution, and
Ji Wei, Qian Zhijie, Xu Bo, Zhao Dean
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A Patent-Based Technology Roadmap for AI-Powered Manipulators: An Evolutionary Analysis of the B25J Classification

open access: yesInformatics
Technology roadmapping is conducted by systematic mapping of technological evolution through patent analytics to inform innovation strategies. This study proposes an integrated framework combining hierarchical Latent Dirichlet Allocation (LDA) modeling ...
Yujia Zhai   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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