Results 51 to 60 of about 47,514 (263)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Assessing Measurement Equivalence in Ordered-Categorical Data

open access: yesPsicológica, 2012
La invarianza factorial estudia de la equivalencia métrica en el marco del modelo lineal del factor común por medio de la comparación de los parámetros del modelo de medida en los grupos de interés.
Paula Elosua
doaj  

Risk Measurement with Equivalent Utility Principles [PDF]

open access: yesSSRN Electronic Journal, 2006
SUMMARY Risk measures have been studied for several decades in the actuarial literature, where they appeared under the guise of premium calculation principles. Risk measures and properties that risk measures should satisfy have recently received considerable attention in the financial mathematics literature.
Denuit, Michel   +4 more
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Testing for measurement equivalence of individuals’ left-right orientation

open access: yesSurvey Research Methods, 2011
Subjective variables such as opinions, attitudes or preferences cannot be measured directly. Researchers have to rely on the answers people give in surveys, and whenever those answers shall be compared it is required that people answer these questions in
Wiebke Weber
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Assessing Measurement Equivalence in Ordered-Categorical Data

open access: yesPsicológica, 2011
La invarianza factorial estudia de la equivalencia métrica en el marco del modelo lineal del factor común por medio de la comparación de los parámetros del modelo de medida en los grupos de interés.
Paula Elosua
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Reference material comparisons: design of experiment and processing of measurement results

open access: yesСтандартные образцы, 2017
The present article describes general principles of experimental research and processing of measurement results within the framework of one of the methods of evaluating the interchangeability of reference materials - paired comparisons of reference ...
E. V. Osintseva
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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