Results 121 to 130 of about 3,328,134 (337)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Research of Tooth Profile Error Evaluation Method based on Cartesian Coordinate Measurement Method

open access: yesJixie chuandong, 2016
The tooth profile error is one important individual errors of gear,with wide use of the coordinate measuring machine in gear measurement,the Cartesian coordinate measuring method is becoming more and more widely applied in gear error measurement field ...
Zhang Bai, Lin Jiachun
doaj  

Measurement error in a single regressor [PDF]

open access: yes
For the setting of multiple regression with measurement error in a single regressor, we present some very simple formulas to assess the result that one may expect when correcting for measurement error. It is shown where the corrected estimated regression
Meijer, E., Wansbeek, T.
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Measurement Error in Access to Markets [PDF]

open access: yes
Studies in the microeconometric literature increasingly utilize distance to or time to reach markets or social services as determinants of economic issues.
Javier Escobal, Sonia Laszlo
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Parametrical synthesis of the existential signals identification device in cross-correlation passive radars

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
Recalculation of measurement time delay differences errors in measurement azimuth and range errors is made. The technique of parameters definition of identification azimuth and range strobes in existential interitem signals identification device is ...
A. A. Dmitrenko, S. Yu. Sedushev
doaj  

Home - About - Disclaimer - Privacy