Results 51 to 60 of about 1,746,399 (312)

Negative association in uniform forests and connected graphs

open access: yes, 2003
We consider three probability measures on subsets of edges of a given finite graph $G$, namely those which govern, respectively, a uniform forest, a uniform spanning tree, and a uniform connected subgraph. A conjecture concerning the negative association
Grimmett, G. R., Winkler, S. N.
core   +6 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Treatment of Hidradenitis Suppurativa Evaluation Study: the THESEUS prospective cohort study

open access: yesHealth Technology Assessment, 2023
Background Hidradenitis suppurativa is a chronic inflammatory skin disease characterised by recurrent inflammatory lesions and skin tunnels in flexural sites such as the axilla.
John R Ingram   +14 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Neurobehavioral response to increased treatment dosage in chronic, severe aphasia

open access: yesFrontiers in Psychology, 2014
Introduction Intensive aphasia treatment has been employed with equivocal results likely due in part to variability in the severity of participants as well as in the parameters that comprise intensity (e.g., session duration).
Jennifer L Mozeiko, Emily B. Myers
doaj   +1 more source

Effect of multiple risk behaviours in adolescence on educational attainment at age 16 years: a UK birth cohort study

open access: yesBMJ Open, 2017
Objectives To explore the association between adolescent multiple risk behaviours (MRBs) and educational attainment. Design Prospective population-based UK birth cohort study.
C. Wright   +4 more
semanticscholar   +1 more source

The Enhanced Reading Opportunities Study: Early Impact and Implementation Findings [PDF]

open access: yes, 2008
This report presents early findings from a demonstration and random assignment evaluation of two supplemental literacy programs that aim to improve the reading comprehension skills and school performance of struggling ninth-grade readers. On average, the
Elizabeth Nelson   +5 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Role of eperisone as an oral analgesic adjunct after arthroscopic rotator cuff repair

open access: yesJournal of Orthopaedic Reports
Background: Inadequate pain relief during the early post-operative stages following arthroscopic shoulder procedures may lead to patients having poor functional and satisfaction outcomes.
Cheryl Gatot   +4 more
doaj   +1 more source

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