Results 61 to 70 of about 1,746,399 (312)

Energy Drink Doses Of Caffeine And Taurine Have A Null Or Negative Effect On Sprint Performance.

open access: yesJournal of Strength and Conditioning Research, 2017
This study investigated the effects of caffeine and taurine co-ingestion on repeat-sprint cycling performance and associated physiological and perceptual responses.
Owen Jeffries   +3 more
semanticscholar   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Exploring differential item functioning in the SF-36 by demographic, clinical, psychological and social factors in an osteoarthritis population [PDF]

open access: yes, 2013
The SF-36 is a very commonly used generic measure of health outcome in osteoarthritis (OA). An important, but frequently overlooked, aspect of validating health outcome measures is to establish if items work in the same way across subgroup of a ...
A Williams   +34 more
core   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Effective pre-school, primary and secondary education project (EPPSE 3-14) : influences on students' attainment and progress in key stage 3 : academic outcomes in English, maths and science in year 9 [PDF]

open access: yes, 2011
The Effective Pre-school, Primary and Secondary Education Project (EPPSE) has investigated the academic and social-behavioural development of approximately 3,000 children from the age of 3+ years since 1997.
Draghici, Diana   +7 more
core   +2 more sources

A Noninformative Prior on a Space of Distribution Functions

open access: yes, 2017
In a given problem, the Bayesian statistical paradigm requires the specification of a prior distribution that quantifies relevant information about the unknowns of main interest external to the data.
Draper, David, Terenin, Alexander
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Understanding the U.S. Economy for Racial Healing

open access: yesHealth Equity, 2023
This article will present a very short discussion of the importance of economics to understanding and eliminating racial hierarchy. Its examples are primarily based on the African American experience.
doaj   +1 more source

A note on confirmation and Matthew properties [PDF]

open access: yes, 2014
There are numerous (Bayesian) confirmation measures in the literature. Festa provides a formal characterization of a certain class of such measures. He calls the members of this class “incremental measures”.
William, Roche
core  

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