Results 1 to 10 of about 6,975,086 (253)

Impairments of mecA gene detection in bovine Staphylococcus spp. [PDF]

Braz J Microbiol, 2014
Staphylococcus aureus antimicrobial resistance, especially to beta-lactams, favors treatment failures and its persistence in herd environment. This work aimed to develop a more specific primer for mecA gene detection based on the comparison of the ...
de Melo DA, Coelho Ida S, da Motta CC, Rojas AC, Dubenczuk FC, Coelho Sde M, de Souza MM.   +6 more
europepmc   +7 more sources

Antibiotic Susceptibility, Biofilm Production, and Detection of mecA Gene among Staphylococcus aureus Isolates from Different Clinical Specimens. [PDF]

Diseases, 2021
The increasing incidence of methicillin-resistant and biofilm-forming S. aureus isolates in hospital settings is a gruesome concern today. The main objectives of this study were to determine the burden of S.
Gaire U, Thapa Shrestha U, Adhikari S, Adhikari N, Bastola A, Rijal KR, Ghimire P, Banjara MR.   +7 more
europepmc   +2 more sources

Methods of detection and typing of methicillin resistant Staphylococcus aureus isolated from animals [PDF]

Veterinarski Glasnik, 2014
In this work there was evaluated the method of detection of methicillin resistant Staphylococcus aureus (MRSA) by using two molecular and three phenotypic tests in investigation procedure of 70 strains of S.aureus isolated from animals.
Radosavljević V., Žutić Jadranka, Pavlović Ljiljana, Bošković Tamara, Radanović O., Žutić M.   +5 more
doaj   +4 more sources

Detection of <i>mec</i>A gene and methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) isolated from milk and risk factors from farms in Probolinggo, Indonesia. [PDF]

F1000Res, 2022
Background: Staphylococcus aureus is commonly found in dairy cows and is a source of contamination in milk. S. aureus that are resistant to beta-lactam antibiotics (especially cefoxitin) are referred to as methicillin-resistant Staphylococcus aureus ...
Rafif Khairullah A, Rehman S, Agus Sudjarwo S, Helmi Effendi M, Chasyer Ramandinianto S, Aega Gololodo M, Widodo A, Hendriana Priscilia Riwu K, Ayu Kurniawati D.   +8 more
europepmc   +2 more sources

Evidence for the evolutionary steps leading to mecA-mediated β-lactam resistance in staphylococci. [PDF]

PLoS Genetics, 2017
The epidemiologically most important mechanism of antibiotic resistance in Staphylococcus aureus is associated with mecA-an acquired gene encoding an extra penicillin-binding protein (PBP2a) with low affinity to virtually all β-lactams.
Joana Rolo, Peder Worning, Jesper Boye Nielsen, Rita Sobral, Rory Bowden, Ons Bouchami, Peter Damborg, Luca Guardabassi, Vincent Perreten, Henrik Westh, Alexander Tomasz, Hermínia de Lencastre, Maria Miragaia   +12 more
doaj   +9 more sources

Antibiotic Resistance and mecA Gene Characterization of Coagulase-negative Staphylococci Isolated from Clinical Samples in Nepal. [PDF]

Infect Drug Resist, 2020
Background Coagulase-negative Staphylococci (CoNS) are a significant cause of hospital-acquired and foreign-body-related infections. We conducted this research to assess methicillin susceptibility of CoNS by disc diffusion, agar dilution, and polymerase ...
Shrestha LB, Bhattarai NR, Rai K, Khanal B.   +3 more
europepmc   +2 more sources

Detection of the mecA gene and identification of Staphylococcus directly from blood culture bottles by multiplex polymerase chain reaction. [PDF]

Braz J Infect Dis, 2018
Introduction Staphylococcus spp. – both S. aureus, including methicillin-resistant strains (MRSA) and coagulase negative staphylococci (CoNS) – are relevant agents of healthcare-associated infections.
Rocchetti TT, Martins KB, Martins PYF, Oliveira RA, Mondelli AL, Fortaleza CMCB, Cunha MLRSD.   +6 more
europepmc   +2 more sources

Methicillin-resistance in Staphylococcus aureus is not affected by the overexpression in trans of the mecA gene repressor: a surprising observation. [PDF]

PLoS ONE, 2011
Methicillin-resistant Staphylococcus aureus (MRSA) is intrinsically cross-resistant to virtually all β-lactam antibiotics. The central determinant for the MRSA phenotype is the mecA gene, whose transcriptional control may be mediated by a repressor (mecI)
Duarte C Oliveira, Hermínia de Lencastre   +1 more
doaj   +2 more sources

Computational Screening of Approved Drugs for Inhibition of the Antibiotic Resistance Gene mecA in Methicillin-Resistant Staphylococcus aureus (MRSA) Strains

BioTech, 2023
Antibiotic resistance is a critical problem that results in a high morbidity and mortality rate. The process of discovering new chemotherapy and antibiotics is challenging, expensive, and time-consuming, with only a few getting approved for clinical use.
Benson Otarigho, Mofolusho O. Falade
doaj   +2 more sources

Screening for mecA and mecC Gene Carriage among Clinical Isolates of Methicillin Resistant Staphylococcus aureus at a Tertiary Care Hospital: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Staphylococcus aureus (S. aureus) has emerged as one of the most important human pathogen, and has been a leading cause of hospital and community acquired infections. Methicillin-Resistant Staphylococcus aureus (MRSA) carrying the mecA gene
Rakshita Ramesh, Deepa Sinha, R Ambica, GB Shantala   +3 more
doaj   +1 more source