Results 11 to 20 of about 13,212 (177)

SNP Scanning in mecA Gene for Methicillin-Resistant Staphylococcus aureus. [PDF]

Iran J Biotechnol, 2020
Staphylococcus aureus (SA) is known as an important human pathogen, which is responsible for many cases of both hospital and community-acquired infections all over the world. Studying on drug resistance is regarded as an important prevention strategy regarding these types of infections.The current study is aimed to assess the association between the ...
Salehi M, Abdolhamid Angaji S, Mosavari N, Ahrabi M.   +3 more
europepmc   +3 more sources

A potential role of transposon IS431 in the loss of mecA gene. [PDF]

Sci Rep, 2017
AbstractAcquisition of a vancomycin-resistance-determinant may trigger deletion of the mecA gene. However, the molecular mechanisms involved remain largely unknown. In this study, we successfully produced vancomycin-intermediate-resistant Staphylococcus aureus (VISA) from Methicillin-resistant-S.
Wang A, Zhou K, Liu Y, Yang L, Zhang Q, Guan J, Zhong N, Zhuo C.   +7 more
europepmc   +4 more sources

Impairments of mecA gene detection in bovine Staphylococcus spp. [PDF]

Braz J Microbiol, 2014
Staphylococcus aureus antimicrobial resistance, especially to beta-lactams, favors treatment failures and its persistence in herd environment. This work aimed to develop a more specific primer for mecA gene detection based on the comparison of the conserved regions from distinct host origins and also investigated the presence of homologue mecA(LGA251 ...
de Melo DA, Coelho Ida S, da Motta CC, Rojas AC, Dubenczuk FC, Coelho Sde M, de Souza MM.   +6 more
europepmc   +6 more sources

Guidelines for Reporting Novel mecA Gene Homologues [PDF]

Antimicrobial Agents and Chemotherapy, 2012
Methicillin-resistant staphylococci are disseminated all over the world and are frequent causes of health care- and community-associated infections. Methicillin-resistant strains typically carry the acquired mecA gene that encodes a low-affinity penicillin-binding protein (PBP), designated PBP2a ...
Ito, T., Hiramatsu, K., Tomasz, A., de Lencastre, H., Perreten, V., Holden, M., Coleman, D., Goering, R., Giffard, P., Skov, R., Zhang, K., Westh, H., O'Brien, Frances, Tenover, F., Oliveira, D., Boyle-Vavra, S., Laurent, F., Kearns, A., Kreiswirth, B., Kwan, S., Grundmann, H., Sollid, J., John, J., Daum, R., Soderquist, B., Buist, G.   +25 more
openaire   +5 more sources

Detection of the Staphylococcal mecA gene by chemiluminescent DNA hybridization [PDF]

Journal of Clinical Microbiology, 1995
A new solution-phase DNA hybridization capture assay for the rapid detection of the mecA gene in clinical isolates of Staphylococcus was compared with multiplex PCR and disk diffusion methods. The assay uses a DNA capture probe immobilized on paramagnetic particles and a second DNA probe labeled with an acridinium ester. Bacteria from 24-h cultures are
C P, Kolbert, J E, Connolly, M J, Lee, D H, Persing   +3 more
openaire   +2 more sources

Systemic Analysis of the mecA Gene Using a Bioinformatics Tool [PDF]

Open Forum Infect Dis, 2017
BACKGROUND: The mecA gene, carried by methicillin-resistant Staphylococcus aureus (MRSA), allows the bacterium to promotes bacterial resistance to antibiotics such as methicillin, penicillin, and other penicillin-like antibiotics. Our objectives are to use a bioinformatics tool to analyze the sequence of the mecA gene, which is spread on the SCCmec ...
Tsai S, Chang F, Ma K, Hsu C, Tung P, Hung Y, Chou Y, Kuo C.   +7 more
europepmc   +3 more sources

Primer Design and Analysis for Detection of mecA gene

Journal of Tropical Pharmacy and Chemistry, 2021
MecA is a gene that causes antibiotic resistance and it contained in Staphylococcus aureus. The gene can be detected using pairs of primer (forward and reverse). Primes is short nucleotide that are used as attachment point for DNA polymerase and as a barrier for the fragment DNA target to be amplified with Polymerase Chain Reaction (PCR).
Armini Syamsidi, Nuur Aanisah, Reyhan Fiqram, Imanuel Al Jultri   +3 more
openaire   +3 more sources

The emerging threat of multidrug-resistant <i>mecA</i> gene-positive coagulase-negative Staphylococci. [PDF]

Iran J Microbiol
Background and Objectives: Coagulase-negative staphylococci (CoNS), previously classified as normal bacterial flora, have recently been associated with serious infectious diseases. The clinical isolation rate of these bacteria has increased in parallel with a rising prevalence of antibiotic resistance.
Hamid SF, Taha AB, Hussien SQ.
europepmc   +4 more sources

Genetic organization of mecA and mecA-regulatory genes in epidemic methicillin-resistant Staphylococcus aureus from Australia and England [PDF]

Journal of Antimicrobial Chemotherapy, 2002
The mecA gene that encodes methicillin resistance in Staphylococcus aureus may be regulated by the mecR1 and mecI genes, and this region has been referred to as the mec complex. An analysis of these regulatory genes in 35 epidemic methicillin-resistant S.
Lim, T.T., Coombs, G.W., Grubb, W.B.
openaire   +2 more sources

Ceftaroline resistance in Staphylococcus pseudintermedius gene mecA carriers [PDF]

Pesquisa Veterinária Brasileira, 2018
ABSTRACT: Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) being a constant concern, ceftaroline fosamil has been recently approved as a new cephalosporin, active against MRSA, for use in humans; only rare cases of resistance have been reported till date.
Scherer, Carolina B., Botoni, Larissa S., Carvalho, Antônio U., Keller, Kelly M., Costa-Val, Adriane P.   +4 more
openaire   +4 more sources