Results 21 to 30 of about 2,550,078 (167)

Accessibility and Alignment of Trans‐Cleavage Substrates Modulate the Kinetics of Cas12a Ribonucleoprotein

open access: yesAngewandte Chemie, EarlyView.
Two key binding events that collectively determine the catalytic efficiency of trans‐cleavage: (1) the substrate passing through the gap between the REC and NUC domains, determined by Kpass, and (2) the alignment of the substrate with the catalytic triad of the ribonucleoprotein, determined by Kalign.
Jianyu Hu   +3 more
wiley   +2 more sources

Distribution of MecA and Erm Genes among Methicillin-resistant Staphylococcus Aureus with Inducible Resistance to Clindamycin

open access: yesJournal of Nepal Health Research Council, 2023
Background: The emergence of Methicillin-resistant Staphylococcus aureus and its ability to confer cross-resistance to macrolide-lincosamide-streptogramin B has complicated the treatment against it.
Dudha Raj Malla Thakuri   +7 more
doaj   +1 more source

STUDYING THE FREQUENCY OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS THROUGH THE MOLECULAR DETECTION OF MECA

open access: yesThe Iraqi Journal of Medical Sciences, 2016
Background: Methicillin-resistant Staphylococcus aureus is a major cause of serious nosocomial infections and it is very important to have a reliable test to detect these bacteria.
Rafeef Y. Rasheed, Ahmed S. Abdulamir
doaj   +4 more sources

Prevalence and in vitro susceptibility of methicillin-resistant Staphylococcus pseudintermedius (MRSP) from skin and nostrils of dogs with superficial pyoderma

open access: yesPesquisa Veterinária Brasileira
: In order to assess the prevalence of Methicillin-resistant Staphylococcus pseudintermedius from skin and nostrils of dogs with pyoderma, to determine its in vitro susceptibility, and to correlate these data with the presence of the mecA gene, 43 dogs ...
Larissa S. Botoni   +6 more
doaj   +1 more source

Non detection of mecA gene in methicillin resistant Staphylococcus aureus isolates from pigs [PDF]

open access: yes, 2019
Background: Methicillin resistant Staphylococcus aureus (MRSA) have become a global health problem causing infections in both humans and livestock, ranging from skin and soft tissue to life threatening blood stream infections.
Nwaogaraku, C.N.   +2 more
core   +1 more source

Frequency of mecA and blaZ genes in isolates of Staphylococcus aureus isolated from clinical samples by PCR method

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2020
Background and Objective: Staphylococcus aureus (S. aureus) is the most common cause of nosocomial infections. Treatment of Staphylococcal infections has become more complicated due to the emergence of methicillin-resistant S.aureus (MRSA) strains.
Yasaman Rahnama   +2 more
doaj  

Correlation of Minimum Inhibitory Concentration Breakpoints and Methicillin Resistance Gene Carriage in Clinical Isolates of Staphylococcus epidermidis [PDF]

open access: yesIranian Journal of Medical Sciences, 2011
Staphylococcus epidermidis is the most important member of coagulase negative staphylococci responsible for community and hospital acquired infections. Most clinical isolates of S.
Fereshteh Eftekhar,, Fereshteh Raei
doaj  

Virulence, biofilm formation ability and antimicrobial resistance of Staphylococcus aureus isolated from cell phones of university students

open access: yesABCS Health Sciences, 2022
Introduction: Contamination of cell phones can contribute to the dissemination of pathogens in the community and/or hospital environment. Objective: To characterize Staphylococcus aureus strains isolated from cell phones of university students. Methods:
Gabrielle Messias de Souza   +7 more
doaj   +1 more source

Prevalence of mecC Gene in MRSA at A Tertiary Hospital in Medan, Indonesia

open access: yesJournal of Pure and Applied Microbiology
Methicillin-resistant Staphylococcus aureus (MRSA) is resistant to β-lactam antibiotics owing to the presence of mecA and mecC resistance genes. Resistance genes in MRSA are carried by a genetic component named staphylococcal cassette chromosome mec ...
Fiola Elsabillah Amandani   +4 more
doaj   +1 more source

Multi-dimensional genomic analysis of myoepithelial carcinoma identifies prevalent oncogenic gene fusions

open access: yesNature Communications, 2017
Myoepithelial carcinoma (MECA) is a rare aggressive salivary gland cancer. Here, the authors analyze the genomic landscape of MECA and identify a high prevalence of oncogenic gene fusions, primarily PLAG1 fusions, highlighting TGFBR3-PLAG1 as a potential
Martin G. Dalin   +21 more
doaj   +1 more source

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