Results 191 to 200 of about 2,396,468 (298)

Mechanics [PDF]

Osteoarthritis and Cartilage, 2015
openaire   +1 more source

Mechanical contribution of germ cell specification in <i>Arabidopsis</i> anthers. [PDF]

Sci Adv
Liu C, Shi H, Han Y, Wang P, Li K, Zhang Z, Liu J, Zheng Y, Li L, Lin L, Liang C, Qin B, Han H, Bai S, Liu X, Chen W, Zhao F.   +16 more
europepmc   +1 more source

THE MECHANICAL RESTRAINT OF THE INSANE. [PDF]

, 1888
GeorgeH. Savage
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Synthetic mechanoreceptor engineering: From genetic encoding to DNA nanotechnology-based reprogramming. [PDF]

Mechanobiol Med
Yang S, Nie Z.
europepmc   +1 more source

The Electrical Response to Stimulation of Muscle, and its Relation to the Mechanical Response

, 1895
J. Burdon Sanderson
openalex   +2 more sources

An examination of the effects of mechanical shocks and vibrations upon the rate of development of fertilized eggs [PDF]

, 1906
D. D. Whitney
openalex   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Research progress on the role of biomechanical clues in the progression of lung cancer. [PDF]

Front Cell Dev Biol
Gong F, Zhang Q, Fan Q, Qu R, Wang C, Yang T, Fan T, Lv Y, Dai J.   +8 more
europepmc   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source