Results 201 to 210 of about 6,806,810 (337)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Tissue mechanics

The European Physical Journal E, 2022
Kabla, A., Ladoux, B., Di Meglio, J.
openaire   +3 more sources

Morphometric and mechanical evaluation of titanium implant integration: Comparison of five surface structures [PDF]

, 2000
M. Svehla, Per Morberg, B. Zicat, W. Bruce, David H. Sonnabend, William R. Walsh   +5 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Multiple modes of AFM reveal distinct mechanical properties for dystrophin and utrophin not manifest by small fragments. [PDF]

Proc Natl Acad Sci U S A
Hua C, Vavra J, Powers J, Muretta JM, Ervasti JM, Salapaka MV.   +5 more
europepmc   +1 more source

Long-term survival after surgical treatment for post-infarction mechanical complications: results from the Caution study [PDF]

Matteo Matteucci, Daniele Ronco, Mariusz Kowalewski, Giulio Massimi, Michele De Bonis, Francesco Formica, Federica Jiritano, Thierry Folliguet, Nikolaos Bonaros, Sandro Sponga, Piotr Suwalski, Andrea De Martino, Theodor Fischlein, Giovanni Troise, Guglielmo Mario Actis Dato, Giuseppe Filiberto Serraino, Shabir Hussain Shah, Roberto Scrofani, Jurij Matija Kališnik, Andrea Colli, Claudio Russo, Marco Ranucci, Matteo Pettinari, Adam Kowalówka, Matthias Thielmann, Bart Meyns, Fareed Khouqeer, Jean‐François Obadia, Udo Boeken, Caterina Simon, Shiho Naito, Andrea Musazzi, Roberto Lorusso   +32 more
openalex   +1 more source

Mechanical, thermal and tribological properties of polyimide/nano-SiO2 composites synthesized using an in-situ polymerization [PDF]

, 2016
Yuanliang Zhao, Xiaowen Qi, Yu Dong, Jian Ma, Qinglong Zhang, Laizhou Song, Yulin Yang, Qingxiang Yang   +7 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Mechano-mechanical parametric coupling in MEMS between GHz and kHz frequency regimes at room temperature. [PDF]

Microsyst Nanoeng
Kwon M, Arthaber H, Platz D, Schmid U.
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source