Results 261 to 270 of about 915,324 (354)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Mechanical Activation of Graphite for Na-Ion Battery Anodes: Unexpected Reversible Reaction on Solid Electrolyte Interphase via X-Ray Analysis. [PDF]

Adv Sci (Weinh)
Lee SC, Kim YH, Park JH, Susanto D, Kim JY, Han J, Jun SC, Chung KY.   +7 more
europepmc   +1 more source

Structural transformations in the a-tricalcium phosphate powders after mechanical activation and subsequent heat treatment [PDF]

, 2016
V. F. Shamray, A E Karpihin, A. Yu. Fedotov, В. С. Комлев, С. М. Баринов, В. П. Сиротинкин   +5 more
openalex   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Effects of Internal Alkali Activation on Chemical and Mechanical Properties of Fly Ash Cement Systems

, 2016
Phương Trinh Bùi
openalex   +1 more source

Low-Carbon Autoclaved Alkali-Activated Blast Furnace Slag Concrete: Microstructure and Mechanical Properties [PDF]

Carlos Rodriguez, Pablo Gómez, Felipe Martí, Sumit Srivastava, Marina Sánchez, Fernando J. Fraile Fernández, Irene Beleña, Miriam Hernández, Anna Arizzi   +8 more
openalex   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Phase formation, grain structure and electrophysical properties of the mechanically activated ferro-piezoelectric material PCR-8

Denis Zorin, Е. В. Глазунова, I. N. Andryushina, Л. А. Шилкина, А. В. Назаренко, K. P. Andryushin, Ilya A. Verbenko, Л. А. Резниченко   +7 more
openalex   +1 more source

A serial fluoroscopy-guided thrombolytic therapy of a mechanical tricuspid prosthetic valve thrombosis with low-dose and ultra-slow infusion of tissue-type plasminogen activator

, 2014
Macit Kalçık
openalex   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source