Results 31 to 40 of about 2,657,709 (249)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The influence of mix design parameters and compressive strenght on durability indices [PDF]
, 2013 Includes abstract.Current concrete specifications used in mix design are mainly of the prescriptive type, i.e.recipe-based specifications that prescribe limiting values for certain mix design parameters such as minimum binder content, maximum water ...
Angelucci, Matteo
core +1 more source
Energies, 2020 In Poland the use of solid biomass obtained from intentional plantations of energy plants is increasing. This biomass is most often processed into solid fuels. There are growing indications that renewable energy sources, in particular biomass production,
Jakub Styks +3 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Monopoly Distortions in Durability and Multi-Dimensional Quality [PDF]
, 2009 I show that Swan’s (1970) independence result requires a multiplicative interaction between durability and all other quality attributes. Because there is no compelling argument for a multiplicativity in quality, monopolists tend to distort durability ...
Strausz, Roland
core +1 more source
Applied Sciences, 2023 A low-floor train–turnout coupling dynamic model considering bad alignment irregularity ahead of the turnout was established on the basis of a field test in which the dynamic performances of a low-floor train passing through a no.
Xiaohong Jia, Xinwen Yang, Guangtian Shi
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Critical review of the South African Concrete Durability Index tests [PDF]
, 2014 Includes bibliographical references.The Durability Index (DI) approach is a performance-based approach used in South Africa for specifying the durability of reinforced concrete structures with regard to service life and concrete quality.
Mukadam, Zaahir
core +1 more source
Energies, 2020 This paper presents an analysis of selected qualitative characteristics of pellets produced from rape straw obtained from cultivations subjected to different fertilization treatments and from mixtures of straw selected for testing with crude glycerol ...
Magdalena Kachel +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source