Results 51 to 60 of about 2,657,709 (249)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Improving the Mechanical Properties of Mortars by Adding Metal-Doped Zinc Oxide Nanoparticles
Engineering Proceedings, 2023 The evolution of construction engineering depends on the development of cementitious materials with optimized properties and lower environmental impacts, such as the preparation of mortars with higher mechanical resistance and durability.
Max Lima +3 more
doaj +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
FireThe use of agroforestry biomass provides several advantages, both from an environmental point of view, in terms of the mitigation of global warming, and in terms of a circular economy for agricultural or agroforestry companies that reuse pruning residues
Salvatore Francesco Papandrea +6 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
Structural durability- a controversal research field of current interest
, 2022 S.3-7Darmstadt played a key role in the early studies of structural durability, especially through the contributions of Prof. Kurt Klöppel, Prof. August Thum, Prof. Ernst Gaßner.
Hanselka, H.
core +1 more source
Results in Physics, 2020 Silica antireflection coatings from sol-gel processes are of great importance in optical areas because of their capability to reduce light reflection and hence to increase transmission.
Fangting Chi +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao +5 more
wiley +1 more source
Journal of Materials Science: Materials in EngineeringEpoxy coatings for stacked electrical steel are of high relevance for renewable energy and electric mobility technologies. Waterborne epoxy varnish systems for electrical steel laminates are still under development.
Cornelia Marchfelder +2 more
doaj +1 more source
Evaluation of selected properties of briquettes from recovered paper and board
Research in Agricultural Engineering, 2015 Worldwide increasing energy demand is today permanently covered by a majority of non-renewable energy sources, namely by coal, crude oil and natural gas.
M. Brožek
doaj +1 more source