Results 91 to 100 of about 2,411,563 (322)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Composites in Aerospace and Mechanical Engineering. [PDF]
Materials (Basel), 2023 Georgantzinos SK +3 more
europepmc +1 more source
Engineering mechanics and sustainable engineering
, 2021 At a time of significant global environment challenges and need for sustainable development. A new area of Sustainability in design and manufacturing is on the horizon and Engineering Mechanics Curricula need to equip the graduates with theory, knowledge, and applications of this new science.
openaire +1 more source
When mechanical engineering inspired from physiology improves postural-related somatosensory processes [PDF]
, 2022 Chloé Sutter +4 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Heliyon, 2019 Many research works are being carried out to enhance the performances of internal combustion engines to meet out the current energy demand and to reduce the emission with the alternate fuels.
M. Vijayakumar, P.C. Mukesh Kumar
doaj +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Heliyon, 2017 The necessity to increase performances in terms of lifetime and security in mechanical components or structures is the motivation for intense research in fatigue. Applications range from aeronautics to medical devices.
Diogo Montalvão, Andrew Wren
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
When mechanical engineering inspired from physiology improves postural-related somatosensory processes. [PDF]
Sci Rep, 2023 Sutter C +4 more
europepmc +1 more source