Results 91 to 100 of about 665,980 (290)

Effect of nozzle geometry on critical-subcritical flow transitions

open access: yesHeliyon, 2019
The geometry of converging-diverging nozzles affects the conditions at which critical-subcritical flow transition occurs. The objective of this work is to develop guidelines to identify the optimum nozzle geometry that maximizes critical pressure ratio ...
Jagmit Singh   +3 more
doaj  

Openings for Mechanical Engineers in China [PDF]

open access: yesProceedings of the Institution of Mechanical Engineers, 1899
n ...
openaire   +2 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Combustion and emission characteristics of diesel fuel blended with raw jatropha, soybean and waste cooking oils

open access: yesHeliyon, 2019
In the present investigation raw oil (jatropha, soybean, and waste cooking fuel) has analyzed to prove its suitability as an alternative fuel in compression ignition (CI) engines.
Prem Kumar Chaurasiya   +3 more
doaj  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

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