Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Understanding the wire electrical discharge machining of Ti6Al4V alloy
Heliyon, 2019 Non-conventional machining process for instance, wire electrical discharge machining (WEDM) of titanium alloys is gaining attention due to non-contact nature of this process.
A. Pramanik, A.K. Basak, C. Prakash
doaj
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
A novel type of semi-active jet turbulence grid
Heliyon, 2018 This article describes a novel approach to generate increased turbulence levels in an incoming flow. It relies on a cost-effective and robust semi-active jet grid, equipped with flexible tubes as moving elements attached onto tube connections placed at ...
N. Szaszák +5 more
doaj
When mechanical engineering inspired from physiology improves postural-related somatosensory processes. [PDF]
Sci Rep, 2023 Sutter C +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Lubricant flow analysis for effective lubrication of tractor forward/reverse clutch
Heliyon, 2017 Owing to the high power requirements of tractors, their low-power transmission gears often experience durability problems such as burning of the clutch.
Daekyung Noh +3 more
doaj
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Risks related to the lack of lubrication on surface integrity in drilling
Heliyon, 2019 Drilling processes can significantly affect the surface integrity of metallic components. Thus, the control of the drilling process is of great interest for industry to ensure a satisfactory surface behavior.
Mathieu Girinon +7 more
doaj
Retracted: Influence of Nano-Cutting Fluid in New Cutting and Forming Processes on Heat Transfer Performance of Mechanical Engineering. [PDF]
Int J Anal Chem, 2023 Chemistry IJOA.
europepmc +1 more source