Results 71 to 80 of about 2,446,527 (268)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mechanical Engineering: Medium-Sized Companies with Highest Savings Potential [PDF]
The German mechanical engineering industry, dominated by medium-sized companies, is greatly successful - both on the domestic and on the international market.
Alexander S. Kritikos +1 more
core
Optical Transmission Measurements of Explosive Boiling and Liftoff of a Layer of Micron-Scale Water Droplets from a KrF Laser-Heated Si Substrate [PDF]
, 2003 Water plume velocities were measured in air by optical transmission as a function of laser fluence using a KrF laser for explosive boiling and liftoff of a layer of micron-scale waterdroplets from a laser-heated Si substrate of interest for laser ...
Allen, Susan D., Kudryashov, Sergey I.
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Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Laser Ablation of Optically Thin Absorbing Liquid Layer Predeposited onto a Transparent Solid Substrate [PDF]
, 2006 Ablation of optically thin liquid 2-propanol layers of variable thickness on IR-transparent solid Si substrate by a nanosecond CO 2laser has been experimentally studied using time-resolved optical interferometric and microscopy techniques. Basic ablation
Allen, S. D. +4 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Analysis of Adsorbed Contaminants of CaF/sub 2/ Surfaces by Infrared Laser Induced Desorption [PDF]
, 2004 157 nm photolithography technologies are currently under development and have been accepted as the leading candidate for fabrication of the next generation semiconductor devices after 193 nm.
Allen, Susan D. +2 more
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Heliyon, 2019 Many research works are being carried out to enhance the performances of internal combustion engines to meet out the current energy demand and to reduce the emission with the alternate fuels.
M. Vijayakumar, P.C. Mukesh Kumar
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source