Results 81 to 90 of about 2,446,527 (268)
Heliyon, 2017 The necessity to increase performances in terms of lifetime and security in mechanical components or structures is the motivation for intense research in fatigue. Applications range from aeronautics to medical devices.
Diogo Montalvão, Andrew Wren
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Fuels with low octane number: water injection as knock control method
Heliyon, 2019 The present paper deals with the study of water effect on the combustion of fuels with low Octane Number in Internal Combustion Engines. In particular, this study was carried out using a variable volumetric compression ratio CFR fuel engine.ASTM ...
S. Brusca +4 more
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Heliyon, 2019 Background: The Hip joint is the primary joint which gives stability to the human body. The wear and tear associated with age and other factors, require these joints to be replaced by implants using hip arthroplasty surgeries. Cobalt chromium alloy (CoCr)
Chethan K.N. +4 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Keeping a reflective journal : reflections of a mature student [PDF]
, 2001 Reflective journals are used increasingly in Higher Education. Examples from an unstructured journal kept by the author in her role as a new Mechanical Engineering student raise issue of what 'ought' to be in journals, how emotional effects should be ...
Sinclair, C.M.
core
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Quantum Communication Technology
, 2010 Quantum communication is built on a set of disruptive concepts and technologies. It is driven by fascinating physics and by promising applications. It requires a new mix of competencies, from telecom engineering to theoretical physics, from theoretical ...
Gisin, Nicolas, Thew, Rob
core +3 more sources
Composites in Aerospace and Mechanical Engineering. [PDF]
Materials (Basel), 2023 Georgantzinos SK +3 more
europepmc +1 more source