Results 141 to 150 of about 5,213 (312)

Investigation of nickel oxide and germanium for Li-ion battery anodes

, 2014
We aimed to develop high performance anodes for Li-ion batteries. Three approaches were investigated to minimize the aggregation, pulverization and delamination problems.
Rahmat, Agung Susantyoko
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Speed effect on cortical bone Speed effects on the mechanical properties of cortical bone. Challenges for fracture risk prediction?

, 2017
« Open your mind seminar » Biomedical Engineering Master, PARIS, FRANCE, 13-/01/2017 - 13/01/2017David Mitton is interested in fracture risk prediction. He has developed expertise in tissue biomechanics.
Mitton, David
core   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

CAD / ARDUINO INTRODUCTORY WORKSHOPS IN FIRST YEAR ENGINEERING PROJECT-BASED COURSE A WAY TO GET STUDENTS TO DESIGN AND BUILD HIGH QUALITY PROTOTYPES

, 2019
As educators, there are several challenges that we need to overcome during the first-year of our engineering programs. We need to integrate students into the world of engineering and introduce them on practical aspects. We have to connect them with basic
Méthot, Jean-François, Brousseau, Jean
core  

Inclusive and collaborative advanced transport: are we really heading to sustainable mobility?

European Transport Research Review, 2022
Pierluigi Coppola, António Lobo
doaj   +1 more source

Mechanical and tribological properties of Ti-Al-Y-N and Ti-Al-Ta-N coatings deposited by HiPIMS: Influence of the bias voltage

Results in Engineering
Despite extensive research on PVD coatings, few studies explore the use of High-Power Impulse Magnetron Sputtering (HiPIMS) for depositing TiAlYN and TiAlTaN coatings, especially regarding the impact of bias voltage. This study investigates how different
Andresa Baptista, Francisco J.G. Silva, Jacobo Porteiro, Gustavo F. Pinto, Diogo Cavaleiro, Manuel Evaristo, Eduardo Silva, Filipe Fernandes   +7 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Optimal design of a flying-wing aircraft inner wing structure configuration [PDF]

, 2012
Flying-wing aircraft are considered to have great advantages and potentials in aerodynamic performance and weight saving. However, they also have many challenges in design.
Huang, Haidong
core