Results 131 to 140 of about 5,213 (312)
UTILIZATION OF THE PARAMETRIC TRANSPORTATION PROBLEM IN MECHANICAL ENGINEERING [PDF]
The International Conference on Applied Mechanics and Mechanical Engineering, 1984 Said HASSAN, M. OSMAN, A. ABOUEL NOUR
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
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FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
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Mechanical Fatigue of a Stabilized/Treated Soil Tested with Uniaxial and Biaxial Flexural Tests
, 2016 During Civil Engineering works, it is a common practice to upgrade mechanical performances of in situ soils by adding few percent of hydraulic binders such as lime and/or cement. But the specificity of stress state in railways structures (biaxial tension)
Preteseille, Mathieu, Lenoir, Thomas
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
User-centered product design of live-action game experiences
, 2018 Thesis: S.B., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2018.Cataloged from PDF version of thesis.Includes bibliographical references (page 48).Recently, escape rooms, or live-action physical and mental adventure games ...
Orozco, Eduardo, S.B. Massachusetts Institute of Technology
core
Zone conditional modeling of premixed turbulent flames at a high Damkohler number
, 2019 The zone conditioning approach is applied to generic mass and momentum conservation equations in unburned and burned gas. Conditionally averaged equations include additional source terms with flame surface density to reflect interfacial transports ...
Huh, KY, Lee, E
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Economy of Region, 2012 In the article, the transport role in the decision of problems of innovative and scientifically-technological development of territory is defined. Dependence of quality, completeness and timeliness of granting of transport services on replenishment and updating of park of locomotives, cars, i.e.
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
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