Results 71 to 80 of about 344,022 (350)

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Prioritization of hazards by means of a QFD-based procedure [PDF]

, 2018
Despite the evolution of regulations in the field of occupational health and safety promoted in EU countries, the number of accidents and victims has not significantly decreased in recent years, especially in constructions and agriculture sectors, as ...
Fargnoli, Mario, Lombardi, Mara
core   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Identification Methods and Test Results for Tilting Pad and Fixed Geometry Journal Bearing Dynamic Coefficients – A Review

Shock and Vibration, 2009
Fluid film journal bearings (FFBs) are used to support high-speed rotors in turbomachinery which often operate above the rotor first bending critical speed.
T.W. Dimond, P.N. Sheth, P.E. Allaire, M. He   +3 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Monitoring the Joint Area of Composite Membrane Materials

Applied Sciences, 2019
Textile membranes are suitable for a wide range of applications due to their user-adjustable properties, which can be modified based on both the textile reinforcement structure and the coating material. Complex dynamic loads are involved in typical usage
Hans Winger, Oliver Döbrich, Hassan Saeed, Thomas Gereke, Andreas Nocke, Chokri Cherif   +5 more
doaj   +1 more source

Machine Learning Analysis in Mechanical Engineering

Computers and artificial intelligence
Despite the rapid development of the AI industry and the programming industry in the machinery manufacturing or production industry, there is no systematic explanation as to why the use of machine learning can enhance the development of related ...
Huangyu Zhao
semanticscholar   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Methods of Testing of Roller Rotational Resistance in Aspect of Energy Consumption of a Belt Conveyor

Energies, 2022
The testing of roller rotational resistance is essential in improving and searching for new design solutions to reduce the energy consumption of belt transport.
Piotr Kulinowski, Piotr Kasza, Jacek Zarzycki   +2 more
doaj   +1 more source

Risk evaluation for RoPax vessels [PDF]

, 2008
The paper presents the results of a recent risk evalua-tion study for RoPax vessels, carried out as part of the activities of the SAFEDOR Integrated Project.
Konovessis, Dimitris, Vassalos, Dracos
core   +1 more source