Results 101 to 110 of about 3,580,269 (281)

Shaping leaf vein pattern by auxin and mechanical feedback. [PDF]

open access: yesJ Exp Bot, 2021
Burian A   +2 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Conversational Feedback

open access: yes, 2012
This site is about the ANR project "Conversational Feedback". In a conversation, feedback is mostly performed through short utterances produced by another participant than the main current speaker.
Laurent Prévot
core   +1 more source

Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle. [PDF]

open access: yesNat Commun, 2021
Avellaneda J   +6 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Characterization of Dynamic Gripping Force Feedback for Robot-Assisted Surgery

open access: yesCurrent Directions in Biomedical Engineering
Haptic feedback of gripping forces during robotassisted surgery can benefit the surgical outcome by means of reduced forces applied to the tissue. A custom-designed haptic user interface allows to control four degrees of freedom of the instrument’s ...
Schäfer Max B.   +7 more
doaj   +1 more source

Modeling autoregulation of cardiac excitation-Ca-contraction and arrhythmogenic activities in response to mechanical load changes

open access: yesiScience
Summary: The heart has intrinsic abilities to autoregulate contractile force in response to mechanical load. Recent experimental studies show that cardiomyocytes have mechano-chemo-transduction (MCT) mechanisms that form a closed feedback loop in the ...
Asuka Hatano   +3 more
doaj   +1 more source

Squeezing of mechanical motion via qubit-assisted control

open access: yesNew Journal of Physics, 2015
We propose a feedback control mechanism for the squeezing of the phononic mode of a mechanical oscillator. We show how, under appropriate working conditions, a simple adiabatic approach is able to induce mechanical squeezing.
Marco G Genoni   +4 more
doaj   +1 more source

Mechanical feedback and robustness of apical constrictions in Drosophila embryo ventral furrow formation. [PDF]

open access: yesPLoS Comput Biol, 2021
Holcomb MC   +6 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

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