Results 91 to 100 of about 164,242 (252)

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

An industrial application for velocity sensor like air type anti-vibration apparatus

open access: yesNihon Kikai Gakkai ronbunshu, 2015
This paper presents an industrial application for an air type anti-vibration apparatus based on the consideration of difference between its apparatus and a velocity sensor.
Shinji WAKUI, Takanobu KUBOTA
doaj   +1 more source

Pitx2 patterns an accelerator-brake mechanical feedback through latent TGFβ to rotate the gut. [PDF]

open access: yesScience, 2022
Sanketi BD   +8 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Passivity-based control of mechanical systems [PDF]

open access: yes, 2017
Stabilization of mechanical systems by shaping their energy function is a well-established technique whose roots date back to the work of Lagrange and Dirichlet.
Romero Velazquez, Jose Guadalupe   +6 more
core   +1 more source

Mechanical feedback drives asynchronous cell divisions during embryogenesis

open access: yesPhysical Review Research
The initial stage of zebrafish morphogenesis is characterized by a synchronous to asynchronous transition (SAT) in cell divisions. The cells divide in unison in the synchronous phase, unlike in the asynchronous phase.
Abdul N. Malmi-Kakkada   +2 more
doaj   +1 more source

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