Results 61 to 70 of about 3,580,269 (281)

Broadcast Feedback As Causal Mechanisms For Migration

open access: yes, 2015
Abstract This paper is based on the findings of the Theorizing the Evolution of European Migration Systems (THEMIS) project, which explores how the migration of people at one point in time affects subsequent patterns of migration to the same area. It focuses on the feedback processes: the social mechanisms that link migration experiences across time ...
Bakewell, Oliver, Jolivet, Dominique
openaire   +4 more sources

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Entropy injection as a global feedback mechanism [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2003
10 pages, submitted to ...
Oh, S. Peng, Benson, Andrew
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Controllable branching of robust response patterns in nonlinear mechanical resonators

open access: yesNature Communications, 2023
Feedback control applied to mechanical resonators can lead to the formation of various complex dynamic behaviors. Here the authors demonstrate flexible and controllable switching between dynamical structures in the response of harmonically driven micro ...
Axel M. Eriksson   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Nonlinear Output Feedback Control: An Analysis of Performance and Robustness [PDF]

open access: yes, 2004
By considering a non-singular performance cost functional, observer backstepping designs and adaptive observer backstepping designs are compared to high-gain observer designs for an output feedback system and a parametric output feedback system.
Xie, Chengkang
core   +1 more source

Targeted feedback for Indonesian-speaking classrooms in higher education context: A perspective from educators’ lens [PDF]

open access: yes
In today's interconnected world, excellent communication is essential to develop relationships and cooperate with people from various cultural backgrounds.
Rozanah Katrina Herda,Ihtiara Fitrianingsih,Dalwinder Kaur
core   +1 more source

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