Results 51 to 60 of about 1,797,968 (302)

Targeting Mechano-Transcription Process as Therapeutic Intervention in Gastrointestinal Disorders

open access: yesFrontiers in Pharmacology, 2021
Mechano-transcription is a process whereby mechanical stress alters gene expression. The gastrointestinal (GI) tract is composed of a series of hollow organs, often encountered by transient or persistent mechanical stress.
Ramasatyaveni Geesala   +3 more
doaj   +1 more source

Mechanical growth and morphogenesis of seashells [PDF]

open access: yesJournal of Theoretical Biology, 2012
Seashells grow through the local deposition of mass along the aperture. Many mathematical descriptions of the shapes of shells have been provided over the years, and the basic logarithmic coiling seen in mollusks can be simulated with few parameters.
Moulton, D.E., Goriely, A., Chirat, R.
openaire   +7 more sources

Collisions between sintered icy aggregates [PDF]

open access: yes, 2017
Collisions between sintered icy dust aggregates are numerically simulated. If the temperature of an icy aggregate is sufficiently high, sintering promotes molecular transport and a neck between adjacent grains grows.
73382   +3 more
core   +2 more sources

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Circularity potentials, influential factors, modeling approach and policy interventions of circular supply chain for electric vehicles

open access: yesCleaner Engineering and Technology
Electric vehicles (EVs) provide a primary alternative for mitigating greenhouse gas emissions in the transportation sector. Nonetheless, their extensive use poses concerns, including a rise in throwaway batteries, which, if inadequately managed, may ...
Karsi Widiawati   +3 more
doaj   +1 more source

Mechanisms of Stranski-Krastanov growth [PDF]

open access: yesJournal of Applied Physics, 2012
Stranski-Krastanov (SK) growth is reported experimentally as the growth mode that is responsible for the transition to three dimensional islands in heteroepitaxial growth. A kinetic Monte Carlo (KMC) model is proposed that can replicate many of the experimentally observed features of this growth mode.
Baskaran, Arvind, Smereka, Peter
openaire   +2 more sources

Study of a pair of coupled continuum equations modeling surface growth

open access: yes, 2002
In this communication we introduce a pair of coupled continuum equations to model overlayer growth with evaporation-accretion due to thermal or mechanical agitations of the substrate.
Abhijit Mookerjee   +4 more
core   +1 more source

Morphology of Proliferating Epithelial Cellular Tissue [PDF]

open access: yes, 2018
We investigate morphologies of proliferating cellular tissue using a newly developed numerical simulation model for mechanical cell division. The model reproduces structures of simple multi-cellular organisms via simple rules for selective division and ...
Baumeier, Björn   +3 more
core   +2 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Leachates from weathered polypropylene items, but not from polylactic acid, induce ecotoxicological effects on a marine diatom

open access: yesMicroplastics and Nanoplastics
Plastic items released in the marine environment are subject to weathering processes which alter their surface physiochemical properties, and which can induce the leaching of associated chemicals from the polymer matrix to the aquatic media.
Zhiyue Niu   +10 more
doaj   +1 more source

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