Results 101 to 110 of about 29,278,787 (347)

Novel discrete symmetries in the general N = 2 supersymmetric quantum mechanical model

, 2013
In addition to the usual supersymmetric (SUSY) continuous symmetry transformations for the general N = 2 SUSY quantum mechanical model, we show the existence of a set of novel discrete symmetry transformations for the Lagrangian of the above SUSY quantum
Kumar, R., Malik, R. P.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Force Analysis on Coiled Tubing Plug Drilling Operation in Ultra-Deep Well with Long Horizontal Section

Shiyou jixie
For purpose of accurate landing depth prediction and process safety assessment of coiled tubing （CT） plug drilling operation， considering the factors such as wellbore trajectory， buoyant weight of CT， friction of pipe sleeve， CT buckling and boundary ...
Zhang Yumin, Fu Yue, Qu Baolong, Ma Weiguo, Liu Shaohu, Fu Biwei   +5 more
doaj   +1 more source

A mechanical model for guided motion of mammalian cells

, 2015
We introduce a generic, purely mechanical model for environment sensitive motion of mammalian cells that is applicable to chemotaxis, haptotaxis, and durotaxis as modes of motility.
Beck, Kristof Leon, Bitter, Patrick, Lenz, Peter   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Review on the mechanical models and formulations of embedment of traditional timber joints in Japan

Japan Architectural Review, 2020
This paper reviews recent developments of the mechanical models and formulations for the embedment of traditional timber joints in Japan. In recent decades in Japan, seismic performance evaluation methods of traditional timber buildings have been ...
Hideaki Tanahashi, Yoshiyuki Suzuki
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A novel approach to improving the interfacial strength of 3D printed Al–GNP composites by modifying GNP with MgO

APL Materials
In this study, the MgO-coated graphene nanoplatelets (GNP)-reinforced aluminum matrix AlSi10Mg composites are fabricated by mechanical alloying and a 3D printing process.
Dewan Muhammad Nuruzzaman, AKM Asif Iqbal, Md. Nurul Islam, A. K. M. Parvez Iqbal   +3 more
doaj   +1 more source