Results 81 to 90 of about 861,902 (269)

Dynamic mechanical stimulation of alveolar epithelial-fibroblast models using the Flexcell tension system to study of lung disease mechanisms

open access: yesFrontiers in Medicine
Mechanical strain plays a significant role in lung pathophysiology. Current two-dimensional (2D) in vitro models fail to capture the lung's dynamic mechanical environment.
Safiya Al Yazeedi   +10 more
doaj   +1 more source

Two-Stage Discrete Mechanical Modelin Three-Dimensional Spacefor Garmentsimulation

open access: yesAUTEX Research Journal, 2019
This paper focuses on the better performance between the garment simulation result and the simulation speed. For simplicity and clarity, a notation “PART” is defined to indicate the areas between the garment and the human body satisfying some constraints.
Luo Xuan, Jiang Gaoming, Cong Honglian
doaj   +1 more source

Photocarcinogenesis — models and mechanisms [PDF]

open access: yesPhotodermatology, Photoimmunology & Photomedicine, 1999
H, Mukhtar   +2 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Modeling of human center of pressure using a viscoelastic-supported inverted pendulum

open access: yesMechanical Engineering Journal
Preventing falls is crucial for the elderly, and as an initial step, accurately quantifying their current balance abilities is essential. In this regard, the Center of Pressure (COP) has gained attention.
Yoshikazu YAMANAKA, Katsutoshi YOSHIDA
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Load Analysis and Calculation of Makeup and Breakout Device on Continuous Circulation System

open access: yesShiyou jixie, 2019
The makeup and breakout device is a key component of the continuous circulation system. To rationally design the makeup and breakout device on the continuous circulation system, the working principle and operation procedure are analyzed. According to the
Hu Zhijian, Ma Qingfang, Liu Jiliang
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Application and Node Mechanics Analysis of Sucker Rod Pump Injection-production System

open access: yesShiyou jixie, 2017
To achieve effective production stabilization and water-cut control in extra-high water-cut wells, a sucker rod pump injection-production system has been designed. The system uses gravity to separate the oil and water in the downhole. The separated water
Jiang Minzheng   +3 more
doaj  

Failure depths of stope floors under dynamic loading induced by roof breaking

open access: yesMeitian dizhi yu kantan
ObjectiveAccurately assessing the failure depths of stope floors is crucial for assessing floor water inrush risks. Conventional theoretical models for calculating the failure depths generally merely consider static loads from the support pressure and ...
Qisong HUANG   +5 more
doaj   +1 more source

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