Results 91 to 100 of about 29,278,787 (347)

Numerical Study on the Flexural Performance of Fully Bolted Joint for Panelized Steel Modular Structure

Buildings
To investigate the initial rotational stiffness and ultimate moment of fully bolted connections in panelized steel modular structures, a finite element analysis was carried out on 20 joint models.
Hao Wang, Xuetong Li, Conghe Tian, Jintao Cui, Xuyue Wang, Chuan Zhao, Yanlai Li   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Experimental Study on Local Bearing Capacity of Concrete Reinforced with Spiral Stirrups

Buildings
To investigate the local compressive bearing capacity of concrete reinforced with spiral stirrups, a study was conducted on 40 specimens, focusing on the analysis of failure modes and strain variations.
Hongbo Li, Ying Zhou, Shanshan Wang, Yongjian Ding, Deyu Jiang, Tianming Miao, Ruchen Qie, Xin Bao, Yongmei Qian, Bo Wang   +9 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Static Model of the Middle Ear Subjected to Reconstruction by Using the “Large Island” Tympanoplasty Technology. Part II: Strain-Stress State

Механика машин, механизмов и материалов, 2009
The mathematical and mechanical model of the reconstructed middle ear subjected to tympanoplasty by using the "large island" technique is constructed. The restored tympanic membrane (TM) is modeled as the system of two concentrically conjugate annular ...
G.I. Mikhasev , S.A. Ermochenko
doaj  

Mechanical characteristics of coal pillars in complex-structure coal seams and optimization of roadway surrounding rock stability

河南理工大学学报. 自然科学版
ObjectivesTo address the problems of severe roadway surrounding damage and poor stability during mining of complex-structure coal seams， the failure mechanism of coal pillars under roadway stress was investigated， taking the 10103 face of Baozigou Coal ...
Niu Haiping, Pan Ruikai, Yu Weidong, Shen Yuxu, Wu Shaokang   +4 more
doaj   +1 more source

A fully coupled hydro-mechanical model for the modeling of coalbed methane recovery

, 2017
Most coal seams hold important quantities of methane which is recognized as a valuable energy resource. Coal reservoir is considered not conventional because methane is held adsorbed on the coal surface. Coal is naturally fractured, it is a dual-porosity
F. Bertrand, B. Cerfontaine, F. Collin
semanticscholar   +1 more source

Structure-Based Statistical Mechanical Model Accounts for the Causality and Energetics of Allosteric Communication

PLoS Comput. Biol., 2016
Allostery is one of the pervasive mechanisms through which proteins in living systems carry out enzymatic activity, cell signaling, and metabolism control.
Enrico Guarnera, I. Berezovsky
semanticscholar   +1 more source

A spring-block model for Barkhausen noise

, 2004
A simple mechanical spring-block model is introduced for studying magnetization phenomena and in particularly the Barkhausen noise. The model captures and reproduces the accepted microscopic picture of domain wall movement and pinning.
Burridge R, Durin G, Durin G Zapperi S, K Kovács, Mnyukh J, Y Brechet, Z Néda   +6 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source