Results 71 to 80 of about 27,702,308 (366)

A three-dimensional coupled thermo-hydro-mechanical model for deformable fractured geothermal systems

open access: yes, 2018
A fully coupled thermal-hydraulic-mechanical (THM) finite element model is presented for fractured geothermal reservoirs. Fractures are modelled as surface discontinuities within a three-dimensional matrix. Non-isothermal flow through the rock matrix and
S. Salimzadeh   +3 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Compression and energy absorption properties of the truss-like lightweight materials based on symmetric groups

open access: yesMaterials Research Express, 2023
Truss-like lightweight materials (TLMs) have been widely used in aeronautics and astronautics, because of excellent mechanical property and superior energy absorption capability.
Zhenhao Ma   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Factors Influencing Deviation Correction Capability of Automatic Vertical Drilling Tool

open access: yesShiyou jixie, 2021
Automatic vertical drilling system can solve the poor effect of traditional passive deviation control system. In order to realize effective deviation control and correction of automatic vertical drilling system, the factors influencing the deviation ...
Yang Dengwen   +3 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A DOE and kriging-based model for studying on the dynamics of multibody mechanical systems with revolute joint clearance : draft

open access: yes, 2013
Over the last two decades, extensive work has been done to study the dynamic effect of the joint clearances in multibody mechanical systems. In contrast, little work has been devoted to optimize the performance of these systems.
Flores, Paulo   +8 more
core   +1 more source

Numerical Study on the Flexural Performance of Fully Bolted Joint for Panelized Steel Modular Structure

open access: yesBuildings
To investigate the initial rotational stiffness and ultimate moment of fully bolted connections in panelized steel modular structures, a finite element analysis was carried out on 20 joint models.
Hao Wang   +6 more
doaj   +1 more source

Nonlinear mechanical model of a fluid inerter

open access: yesMechanical systems and signal processing, 2023
M. Chillemi   +3 more
semanticscholar   +1 more source

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